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Open Access

Peer-reviewed

Research Article

The histone modification regulator, SIN3, plays a role in the cellular response to changes in glycolytic flux

Imad Soukar,

Roles Formal analysis, Investigation, Writing – original draft, Writing – review & editing

Affiliation Department of Biological Sciences, Wayne State University, Detroit, Michigan, United States of America
⨯
Anindita Mitra,

Roles Formal analysis, Investigation, Writing – review & editing

Affiliation Department of Biological Sciences, Wayne State University, Detroit, Michigan, United States of America
⨯
Linh Vo,

Roles Formal analysis, Investigation, Writing – review & editing

Affiliation Department of Biological Sciences, Wayne State University, Detroit, Michigan, United States of America

https://orcid.org/0000-0002-0665-0309

⨯
Melanie Rofoo,

Roles Formal analysis, Investigation, Writing – review & editing

Affiliation Department of Biological Sciences, Wayne State University, Detroit, Michigan, United States of America
⨯
Miriam L. Greenberg,

Roles Supervision, Writing – review & editing

Affiliation Department of Biological Sciences, Wayne State University, Detroit, Michigan, United States of America
⨯
Lori A. Pile

Roles Conceptualization, Writing – original draft, Writing – review & editing

* E-mail: loripile@wayne.edu

Affiliation Department of Biological Sciences, Wayne State University, Detroit, Michigan, United States of America

https://orcid.org/0000-0002-7189-4828

⨯

The histone modification regulator, SIN3, plays a role in the cellular response to changes in glycolytic flux

Imad Soukar,
Anindita Mitra,
Linh Vo,
Melanie Rofoo,
Miriam L. Greenberg,
Lori A. Pile

x

Published: November 26, 2025
https://doi.org/10.1371/journal.pone.0335411

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Cell metabolism
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Gene expression
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Drosophila melanogaster
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Gene regulation
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Glucose
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Glycolysis
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Cellular stress responses
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Mitochondria
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