Protocol for an open labelled observational study in children & adolescents with severe asthma with an eosinophilic phenotype treated with mepolizumab (CASAM)

• Atul Gupta ,

  Roles Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing, Data curation, Conceptualization, Investigation, Funding acquisition

  * E-mail: Atul.gupta@kcl.ac.uk

  ¶‡ These authors are joint senior authors on this work.

  Affiliations Paediatric Respiratory Department, King’s College Hospital, Department of Women and Children’s Health, London, United Kingdom, Faculty of Life Sciences and Medicine, King’s College London, London, United Kingdom, 

  https://orcid.org/0000-0002-1610-0335

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• Ines de Mir Messa ,

  Roles Conceptualization, Data curation, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  ¶‡ These authors are joint senior authors on this work.

  Affiliation Hospital Universitari Vall Hebron, Institut de Recerca de l’Hospital Universitari Vall d’Hebron (VHIR), Barcelona, Spain

  https://orcid.org/0000-0002-1418-4563

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• Jose Valverde-Molina,

  Roles Conceptualization, Data curation, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Paediatrics, Santa Lucía General University Hospital, IMIB Biomedical Research Institute, Cartagena, Murcia, Spain

  https://orcid.org/0000-0002-1971-7613

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• Clare S. Murray,

  Roles Data curation, Project administration, Supervision, Writing – review & editing

  Affiliation Division of Immunology, Immunity to Infection and Respiratory Medicine, School of Biological Sciences, The University of Manchester, Manchester Academic Health Science Centre, and Manchester University NHS Foundation Trust, Manchester, United Kingdom

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• Luis Moral,

  Roles Data curation, Project administration, Supervision, Writing – review & editing

  Affiliation Paediatric Allergy and Respiratory Unit, Alicante University General Hospital, Alicante Institute for Health, and Biomedical Research (ISABIAL - FISABIO Foundation), Alicante, Spain

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• Javier Torres Borrego,

  Roles Data curation, Project administration, Supervision, Writing – review & editing

  Affiliation Paediatric Allergy and Respiratory Unit, Children’s University Hospital Reina Sofia, and The Maimonides Institute for Biomedical Research of Cordoba (IMIBIC), Córdoba, Spain

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• Katharine Pike,

  Roles Data curation, Project administration, Supervision, Writing – review & editing

  Affiliation Bristol Royal Hospital for Children, Bristol, United Kingdom

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• Ana Díaz-Izquierdo,

  Roles Data curation, Project administration, Supervision, Writing – review & editing

  Affiliation Hospital Universitari Vall Hebron, Institut de Recerca de l’Hospital Universitari Vall d’Hebron (VHIR), Barcelona, Spain

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• Ana Martínez-Cañavate,

  Roles Data curation, Project administration, Supervision, Writing – review & editing

  Affiliation H.U. Virgen de las Nieves, Granada, Spain

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• Prasad Nagakumar,

  Roles Data curation, Project administration, Supervision, Writing – review & editing

  Affiliation Birmingham Women’s and Children’s Hospital, Birmingham, United Kingdom

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• James Cook,

  Roles Project administration, Supervision, Writing – review & editing, Data curation

  Affiliation Paediatric Respiratory Department, King’s College Hospital, Department of Women and Children’s Health, London, United Kingdom

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• Latika Gupta,

  Roles Data curation, Project administration, Supervision, Writing – review & editing

  Affiliation Paediatric Respiratory Department, King’s College Hospital, Department of Women and Children’s Health, London, United Kingdom

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• On behalf of the CASAM Group

  ¶CASAM Group: Membership of the CASAM Group is provided in the acknowledgments.

  Affiliation Paediatric Respiratory Department, King’s College Hospital, Department of Women and Children’s Health, London, United Kingdom

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