Computational evaluation of AKT2 mutations reveals R274H and R467W as potential drivers of protein instability and inhibitor resistance in cancer therapy

• Sadia Afrin Runa ,

  Contributed equally to this work with: Sadia Afrin Runa, Mahafujul Islam Quadery Tonmoy

  Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft

  Affiliation Department of Biotechnology and Genetic Engineering, Gopalganj Science and Technology University, Gopalganj, Bangladesh

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• Mahafujul Islam Quadery Tonmoy ,

  Contributed equally to this work with: Sadia Afrin Runa, Mahafujul Islam Quadery Tonmoy

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources, Supervision, Writing – review & editing

  * E-mail: tonmoy1311@student.nstu.edu.bd

  Affiliations Department of Biotechnology & Genetic Engineering, Noakhali Science and Technology University, Noakhali, Bangladesh, Computational Biology and Chemistry lab (CBC), Noakhali Science and Technology University, Noakhali, Bangladesh

  https://orcid.org/0000-0003-3911-6871

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• Md. Ashiqul Islam,

  Roles Formal analysis, Methodology, Writing – original draft

  Affiliation Department of Biotechnology & Genetic Engineering, Jahangirnagar University, Savar, Dhaka, Bangladesh

  https://orcid.org/0000-0003-1740-926X

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• Md. Aminul Islam

  Roles Formal analysis, Investigation, Methodology, Writing – original draft

  Affiliation Department of Environmental Science & Disaster Management, Gopalganj Science and Technology University, Gopalganj, Bangladesh

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