Development and validation of a risk prediction algorithm for high-risk populations combining genetic and conventional risk factors of cardiovascular disease

• Tuuli Puusepp ,

  Roles Data curation, Formal analysis, Methodology, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: tuuli.puusepp@ut.ee

  Affiliations Institute of Mathematics and Statistics, University of Tartu,, Institute of Genomics, University of Tartu,

  https://orcid.org/0000-0002-9998-1640

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• Ave Põld,

  Roles Formal analysis, Methodology, Project administration, Writing – original draft, Writing – review & editing

  Affiliation Institute of Family Medicine and Public Health, University of Tartu,

  https://orcid.org/0000-0001-8188-4909

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• Lili Milani,

  Roles Conceptualization, Formal analysis, Funding acquisition, Supervision, Writing – review & editing

  Affiliation Institute of Genomics, University of Tartu,

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• Aet Elken,

  Roles Formal analysis, Funding acquisition, Methodology, Writing – review & editing

  Affiliations Heart Clinic, University of Tartu,, Cardiology Centre, North Estonia Medical Centre

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• Estonian Biobank Research Team ,

  ¶Membership of the Estonian Biobank Research Team is provided in the Acknowledgments.

  Affiliation Institute of Genomics, University of Tartu,

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• Mikk Jürisson,

  Roles Conceptualization, Formal analysis, Funding acquisition, Supervision, Writing – review & editing

  Affiliation Institute of Family Medicine and Public Health, University of Tartu,

  https://orcid.org/0000-0002-4487-7045

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• Krista Fischer

  Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Supervision, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Institute of Mathematics and Statistics, University of Tartu,, Institute of Genomics, University of Tartu,

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