Investigating the common genetic basis between inflammatory bowel disease and metabolic syndrome through genomic structural equation modeling

Pan Shen; Hao Xiong; Qing-Hua Luo; Yi-Fan Ding; Wei Ge; Wu Liao; Lei-Chang Zhang

doi:10.1371/journal.pone.0334456

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Open Access

Peer-reviewed

Research Article

Investigating the common genetic basis between inflammatory bowel disease and metabolic syndrome through genomic structural equation modeling

Pan Shen ,

Contributed equally to this work with: Pan Shen, Hao Xiong

Roles Conceptualization, Data curation, Formal analysis, Methodology, Writing – original draft, Writing – review & editing

Affiliation Clinical Medical College, Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, P.R. China
⨯
Hao Xiong ,

Contributed equally to this work with: Pan Shen, Hao Xiong

Roles Conceptualization, Data curation, Formal analysis, Methodology, Software, Writing – original draft, Writing – review & editing

Affiliation Clinical Medical College, Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, P.R. China
⨯
Qing-Hua Luo,

Roles Data curation, Methodology, Supervision, Writing – original draft

Affiliation Clinical Medical College, Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, P.R. China
⨯
Yi-Fan Ding,

Roles Methodology, Resources, Software, Writing – original draft

Affiliation Clinical Medical College, Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, P.R. China
⨯
Wei Ge,

Roles Conceptualization, Supervision, Validation, Visualization

Affiliations Clinical Medical College, Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, P.R. China, Department of Anorectal Surgery, Affiliated Hospital of Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, P.R. China
⨯
Wu Liao,

Roles Supervision, Validation, Visualization, Writing – review & editing

Affiliations Clinical Medical College, Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, P.R. China, Department of Anorectal Surgery, Affiliated Hospital of Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, P.R. China
⨯
Lei-Chang Zhang

Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

* E-mail: zhangleichang@jxutcm.edu.cn

Affiliations Clinical Medical College, Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, P.R. China, Department of Anorectal Surgery, Affiliated Hospital of Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, P.R. China

https://orcid.org/0009-0005-9503-8267

⨯

Investigating the common genetic basis between inflammatory bowel disease and metabolic syndrome through genomic structural equation modeling

Pan Shen,
Hao Xiong,
Qing-Hua Luo,
Yi-Fan Ding,
Wei Ge,
Wu Liao,
Lei-Chang Zhang

Published: October 16, 2025
https://doi.org/10.1371/journal.pone.0334456

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Single nucleotide polymorphisms
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