Analytical validation of a hybrid-approach combining tumor-informed and tumor-agnostic bespoke ctDNA panel assay for the sensitive detection of minimal residual disease

• Sunghoon Heo ,

  Contributed equally to this work with: Sunghoon Heo, Seon-Kyu Ham

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliation IMBdx, Inc., Seoul, Korea

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• Seon-Kyu Ham ,

  Contributed equally to this work with: Sunghoon Heo, Seon-Kyu Ham

  Roles Conceptualization, Methodology, Writing – original draft, Writing – review & editing

  Affiliation IMBdx, Inc., Seoul, Korea

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• Hayoon Lee,

  Roles Methodology

  Affiliation IMBdx, Inc., Seoul, Korea

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• Bom Han,

  Roles Methodology, Software

  Affiliation IMBdx, Inc., Seoul, Korea

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• Hanseong Roh,

  Roles Investigation

  Affiliation IMBdx, Inc., Seoul, Korea

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• Seongmun Jeong,

  Roles Investigation

  Affiliation IMBdx, Inc., Seoul, Korea

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• Hwang-Phill Kim,

  Roles Funding acquisition, Investigation

  Affiliation IMBdx, Inc., Seoul, Korea

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• Duhee Bang,

  Roles Investigation

  Affiliation Department of Chemistry, Yonsei University, Seoul, Korea

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• Sang-Hyun Song,

  Roles Conceptualization, Funding acquisition, Investigation, Writing – review & editing

  Affiliation IMBdx, Inc., Seoul, Korea

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• Tae-You Kim

  Roles Conceptualization, Supervision

  * E-mail: kimty@snu.ac.kr

  Affiliations IMBdx, Inc., Seoul, Korea, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea, Cancer Research Institute, Seoul National University, Seoul, Korea, Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, Korea

  https://orcid.org/0000-0002-9986-2684

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