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Open Access
Peer-reviewed
Research Article
In vitro toxicity assessment of uranium particulates on different human lung epithelial cell models
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Shepard C. Moore ,
Contributed equally to this work with: Shepard C. Moore, Harshini Mukundan, Jennifer Foster Harris
Roles Data curation, Investigation, Validation, Writing – original draft
Affiliation Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America
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Laura M. Lilley ,
Roles Investigation, Methodology, Supervision, Visualization, Writing – review & editing
Current address: TerraPower LLC, Bellevue, Washington, United States of America
¶‡ LML, JS, MOI, WCE, BLS, GLW, WJO and MEM also contributed equally to this work.
Affiliation Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America
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Julie Strickland ,
Roles Investigation, Methodology
Current address: Lovelace Biomedical Research Institute, Albuquerque, New Mexico, United States of America
¶‡ LML, JS, MOI, WCE, BLS, GLW, WJO and MEM also contributed equally to this work.
Affiliation Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America
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Mohammad Omar Ishak ,
Roles Investigation, Methodology
¶‡ LML, JS, MOI, WCE, BLS, GLW, WJO and MEM also contributed equally to this work.
Affiliation Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America
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William Conor Emberley ,
Roles Investigation, Methodology
Current address: Washington State Department of Agriculture, Olympia, Washington, United States of America
¶‡ LML, JS, MOI, WCE, BLS, GLW, WJO and MEM also contributed equally to this work.
Affiliation Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America
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Brian L. Scott ,
Roles Investigation
¶‡ LML, JS, MOI, WCE, BLS, GLW, WJO and MEM also contributed equally to this work.
Affiliation Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America
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Gregory L. Wagner ,
Roles Formal analysis, Investigation, Methodology, Resources, Supervision, Writing – review & editing
¶‡ LML, JS, MOI, WCE, BLS, GLW, WJO and MEM also contributed equally to this work.
Affiliation Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America
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Warren J. Oldham ,
Roles Data curation, Formal analysis, Investigation, Methodology, Visualization
¶‡ LML, JS, MOI, WCE, BLS, GLW, WJO and MEM also contributed equally to this work.
Affiliation Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America
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Murray E. Moore ,
Roles Investigation, Methodology, Writing – review & editing
¶‡ LML, JS, MOI, WCE, BLS, GLW, WJO and MEM also contributed equally to this work.
Affiliation Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America
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Harshini Mukundan ,
Contributed equally to this work with: Shepard C. Moore, Harshini Mukundan, Jennifer Foster Harris
Roles Conceptualization, Funding acquisition, Methodology, Supervision, Writing – review & editing
Current address: Lawrence Berkeley Laboratory, Berkeley, California, United States of America
Affiliation Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America
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Jennifer Foster Harris
Contributed equally to this work with: Shepard C. Moore, Harshini Mukundan, Jennifer Foster Harris
Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing
* E-mail: jfharris@lanl.gov
Affiliation Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America
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In vitro toxicity assessment of uranium particulates on different human lung epithelial cell models
- Shepard C. Moore,
- Laura M. Lilley,
- Julie Strickland,
- Mohammad Omar Ishak,
- William Conor Emberley,
- Brian L. Scott,
- Gregory L. Wagner,
- Warren J. Oldham,
- Murray E. Moore,
- Harshini Mukundan
- Published: October 31, 2025
- https://doi.org/10.1371/journal.pone.0334247