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Open Access

Peer-reviewed

Research Article

Single-cell sequencing reveals the response mechanisms of vascular endothelial cells to glucocorticoids in diabetic retinopathy

Lingda Wang,

Roles Data curation, Writing – original draft

Affiliation Department of Ophthalmology, Shanxi Eye Hospital Affiliated to Shanxi Medical University, Taiyuan, Shanxi, China
⨯
Rong Zhang,

Roles Data curation

Affiliation Department of Ophthalmology, Shanxi Eye Hospital Affiliated to Shanxi Medical University, Taiyuan, Shanxi, China
⨯
Lin Wang,

Roles Data curation

Affiliation Department of Ophthalmology, Shanxi Eye Hospital Affiliated to Shanxi Medical University, Taiyuan, Shanxi, China
⨯
Yongrui Wang,

Roles Data curation

Affiliation Department of Ophthalmology, Shanxi Eye Hospital Affiliated to Shanxi Medical University, Taiyuan, Shanxi, China
⨯
Xiaodan Zhang,

Roles Data curation

Affiliation Department of Ophthalmology, Shanxi Eye Hospital Affiliated to Shanxi Medical University, Taiyuan, Shanxi, China
⨯
Guohong Zhou

Roles Supervision

* E-mail: guohongzhou2016@163.com

Affiliation Department of Ophthalmology, Shanxi Eye Hospital Affiliated to Shanxi Medical University, Taiyuan, Shanxi, China

https://orcid.org/0009-0005-7020-0790

⨯

Single-cell sequencing reveals the response mechanisms of vascular endothelial cells to glucocorticoids in diabetic retinopathy

Lingda Wang,
Rong Zhang,
Lin Wang,
Yongrui Wang,
Xiaodan Zhang,
Guohong Zhou

x

Published: November 6, 2025
https://doi.org/10.1371/journal.pone.0334230

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Gene expression
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Diabetes mellitus
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Glucocorticoid therapy
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Cell communication
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Endothelial cells
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Inflammation
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Drug interactions
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Gene regulation
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