Suppression of kinesin family member-18A diminishes progression and induces apoptotic cell death of gemcitabine-resistant cholangiocarcinoma cells by modulating PI3K/Akt/mTOR and NF-κB pathways

• Pakornkiat Tanasuka,

  Roles Conceptualization, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliations Department of Pathology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand, Cholangiocarcinoma Research Institute, Khon Kaen University, Khon Kaen, Thailand

  https://orcid.org/0009-0001-9735-028X

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• Phonpilas Thongpon,

  Roles Conceptualization, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliations Cholangiocarcinoma Research Institute, Khon Kaen University, Khon Kaen, Thailand, Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand

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• Sasitorn Chomwong,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliations Department of Pathology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand, Cholangiocarcinoma Research Institute, Khon Kaen University, Khon Kaen, Thailand

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• Suppakrit Kongsintaweesuk,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliations Cholangiocarcinoma Research Institute, Khon Kaen University, Khon Kaen, Thailand, Biomedical Sciences Program, Graduate School, Khon Kaen University, Khon Kaen, Thailand

  https://orcid.org/0009-0002-6276-5765

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• Somchai Pinlaor,

  Roles Conceptualization, Supervision, Writing – original draft, Writing – review & editing

  Affiliations Cholangiocarcinoma Research Institute, Khon Kaen University, Khon Kaen, Thailand, Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand

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• Thatsanapong Pongking,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation National Phenome Institute, Office of the President, Khon Kaen University, Khon Kaen, Thailand

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• Sasithorn Watcharadetwittaya,

  Roles Conceptualization, Writing – review & editing

  Affiliations Department of Pathology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand, Cholangiocarcinoma Research Institute, Khon Kaen University, Khon Kaen, Thailand

  https://orcid.org/0000-0001-7952-0583

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• Chawalit Pairojkul,

  Roles Conceptualization, Writing – review & editing

  Affiliations Department of Pathology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand, Cholangiocarcinoma Research Institute, Khon Kaen University, Khon Kaen, Thailand

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• Kitti Intuyod

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Writing – original draft, Writing – review & editing

  * E-mail: kittin@kku.ac.th

  Affiliations Department of Pathology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand, Cholangiocarcinoma Research Institute, Khon Kaen University, Khon Kaen, Thailand

  https://orcid.org/0000-0002-1096-9371

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