Machine learning reveals distinct T-cell receptor clusters in plasma cell dyscrasias compared to healthy controls

• David G. Coffey ,

  Contributed equally to this work with: David G. Coffey, Yong Zhang

  Roles Formal analysis, Methodology, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: davidcoffey@miami.edu (DGC); Andrea.Baines@fda.hhs.gov (AB)

  Affiliation Division of Myeloma, Sylvester Comprehensive Cancer Center, University of Miami, Miami, Florida, United States of America

  https://orcid.org/0000-0003-3544-8836

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• Yong Zhang ,

  Contributed equally to this work with: David G. Coffey, Yong Zhang

  Roles Data curation, Formal analysis, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland, United States of America

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• Elizabeth Hill,

  Roles Data curation, Writing – review & editing

  Affiliation Lymphoid Malignancies Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America

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• Frank Cross Jr.,

  Roles Project administration

  Affiliation Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland, United States of America

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• Reena Philip,

  Roles Supervision, Writing – review & editing

  Affiliation Oncology Center of Excellence, US Food and Drug Administration, Silver Spring, Maryland, United States of America

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• Marc R. Theoret,

  Roles Writing – review & editing

  Affiliations Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland, United States of America, Oncology Center of Excellence, US Food and Drug Administration, Silver Spring, Maryland, United States of America

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• Ola Landgren,

  Roles Writing – review & editing

  Affiliation Division of Myeloma, Sylvester Comprehensive Cancer Center, University of Miami, Miami, Florida, United States of America

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• Andrea C. Baines ,

  Roles Conceptualization, Writing – review & editing

  * E-mail: davidcoffey@miami.edu (DGC); Andrea.Baines@fda.hhs.gov (AB)

  Affiliation Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland, United States of America

  https://orcid.org/0000-0002-9372-415X

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• Dickran Kazandjian

  Roles Conceptualization, Writing – review & editing

  Affiliation Division of Myeloma, Sylvester Comprehensive Cancer Center, University of Miami, Miami, Florida, United States of America

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