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Open Access

Peer-reviewed

Research Article

Serum biomarkers for predicting Crohn’s disease activity: The role of bilirubin, uric acid, and the C-reactive protein/albumin ratio

Ting Xu,

Roles Data curation, Formal analysis, Investigation, Methodology, Resources, Software, Writing – original draft

Affiliation Department of Gastroenterology, the Second Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China
⨯
Tingting Yao,

Roles Data curation, Formal analysis, Writing – original draft

Affiliation Department of Gastroenterology, the Second Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China
⨯
Yating Chen,

Roles Data curation, Formal analysis, Writing – original draft

Affiliation Department of Gastroenterology, the Second Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China
⨯
Fan Xu,

Roles Data curation, Formal analysis, Writing – original draft

Affiliation Department of Gastroenterology, the Second Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China
⨯
Chunxia Lu

Roles Conceptualization, Supervision, Visualization, Writing – review & editing

* E-mail: dingdamao1234@126.com

Affiliation Department of Gastroenterology, the Second Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China

https://orcid.org/0009-0002-3642-7578

⨯

Serum biomarkers for predicting Crohn’s disease activity: The role of bilirubin, uric acid, and the C-reactive protein/albumin ratio

Ting Xu,
Tingting Yao,
Yating Chen,
Fan Xu,
Chunxia Lu

x

Published: March 4, 2026
https://doi.org/10.1371/journal.pone.0333855

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Bilirubin
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Albumins
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C-reactive proteins
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Biomarkers
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Crohn's disease
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Uric acid
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Creatinine
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Inflammatory bowel disease
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