Efficient two-step chemoenzymatic conjugation of antibody fragments with reporter compounds by a specific thiol-PEG-amine Linker, HS-PEG-NH₂

• Haruya Sato ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: Sato.Haruya@sysmex.co.jp (HS); mango@tmu.ac.jp (MT)

  Affiliation Central Research Laboratories, Sysmex Corporation, Healthcare Science Hub Tokyo, Tokyo, Japan

  https://orcid.org/0009-0008-0134-3650

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• Yukiko Kataoka,

  Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization

  Affiliation Bio-Diagnostic Reagent Technology Center, Technology Innovation, Sysmex Corporation, Healthcare Science Hub Tokyo, Tokyo, Japan

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• Youichi Nishikawa,

  Roles Conceptualization, Investigation, Supervision, Writing – review & editing

  Affiliation Central Research Laboratories, Sysmex Corporation, Kobe, Hyogo, Japan

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• Daiki Okano,

  Roles Formal analysis, Investigation

  Affiliation Reagent Engineering, Sysmex Corporation, Kobe, Hyogo, Japan

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• Mami Nagai,

  Roles Data curation, Formal analysis, Validation, Visualization

  Affiliation Reagent Engineering, Sysmex Corporation, Healthcare Science Hub Tokyo, Tokyo, Japan

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• Yoshio Yamauchi,

  Roles Data curation, Formal analysis, Methodology, Supervision, Visualization

  Affiliation Department of Chemistry, Graduate School of Science, Tokyo Metropolitan University, Tokyo, Japan

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• Masato Taoka ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: Sato.Haruya@sysmex.co.jp (HS); mango@tmu.ac.jp (MT)

  Affiliation Department of Chemistry, Graduate School of Science, Tokyo Metropolitan University, Tokyo, Japan

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• Katsuki Naitoh

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Strategic Technology Planning, Technology Strategy, Sysmex, Corporation Healthcare Science Hub Tokyo, Tokyo, Japan

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