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Open Access
Peer-reviewed
Research Article
Prevalence and risk factors of gross neurologic deficits in children after severe malaria: A systematic review and meta-analysis
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Allen Eva Okullo ,
Roles Conceptualization, Data curation, Formal analysis, Methodology, Project administration, Supervision, Validation, Writing – original draft, Writing – review & editing
* E-mail: a.e.okullo@amsterdamumc.nl
Affiliations Department of Paediatrics, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands, Global Health Uganda, Kampala, Uganda, Africa Center for Systematic Reviews & Knowledge Translation, College of Health Sciences, Makerere University, Kampala, Uganda
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Simple Ouma,
Roles Data curation, Formal analysis, Methodology, Validation, Writing – review & editing
Affiliations Global Health Uganda, Kampala, Uganda, Department of Paediatrics and Child Health, School of Medicine, College of Health Sciences, Makerere University, Kampala, Uganda
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Chandy C. John,
Roles Conceptualization, Supervision, Validation, Writing – review & editing
Affiliation Ryan White Center for Pediatric Infectious Diseases and Global Health, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
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Michael Boele van Hensbroek,
Roles Conceptualization, Supervision, Validation, Writing – review & editing
Affiliation Department of Paediatrics, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands
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Kevin Ouma Ojiambo,
Roles Data curation, Formal analysis, Methodology, Software, Visualization, Writing – review & editing
Affiliations Africa Center for Systematic Reviews & Knowledge Translation, College of Health Sciences, Makerere University, Kampala, Uganda, Clinical Epidemiology Unit, School of Medicine, College of Health Sciences, Makerere University, Kampala, Uganda
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Caroline Otike,
Roles Data curation, Methodology, Writing – review & editing
Affiliations Africa Center for Systematic Reviews & Knowledge Translation, College of Health Sciences, Makerere University, Kampala, Uganda, Joint Clinical Research Centre, Kampala, Uganda
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Alison Annet Kinengyere,
Roles Data curation, Software, Writing – review & editing
Affiliations Africa Center for Systematic Reviews & Knowledge Translation, College of Health Sciences, Makerere University, Kampala, Uganda, Sir Albert Cook Library, College of Health Sciences, Makerere University, Kampala, Uganda
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Andrea L. Conroy,
Roles Methodology, Visualization, Writing – review & editing
Affiliations Global Health Uganda, Kampala, Uganda, Ryan White Center for Pediatric Infectious Diseases and Global Health, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
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Moses Ocan,
Roles Methodology, Visualization, Writing – review & editing
Affiliations Africa Center for Systematic Reviews & Knowledge Translation, College of Health Sciences, Makerere University, Kampala, Uganda, Department of Pharmacology & Therapeutics, School of Biomedical Sciences, College of Health Sciences, Makerere University, Kampala, Uganda
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Ekwaro A. Obuku,
Roles Methodology, Visualization, Writing – review & editing
Affiliations Africa Center for Systematic Reviews & Knowledge Translation, College of Health Sciences, Makerere University, Kampala, Uganda, Faculty of Epidemiology & Population Health, London School of Hygiene & Tropical Medicine, London, United Kingdom
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Richard Idro
Roles Conceptualization, Supervision, Validation, Writing – review & editing
Affiliation Department of Paediatrics and Child Health, School of Medicine, College of Health Sciences, Makerere University, Kampala, Uganda
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Prevalence and risk factors of gross neurologic deficits in children after severe malaria: A systematic review and meta-analysis
- Allen Eva Okullo,
- Simple Ouma,
- Chandy C. John,
- Michael Boele van Hensbroek,
- Kevin Ouma Ojiambo,
- Caroline Otike,
- Alison Annet Kinengyere,
- Andrea L. Conroy,
- Moses Ocan,
- Ekwaro A. Obuku
- Published: March 17, 2026
- https://doi.org/10.1371/journal.pone.0333258