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Open Access

Peer-reviewed

Research Article

Integrative GWAS and RNA-Seq analysis for target identification and virtual drug screening in colorectal cancer

Qinghui Liu ,

Roles Conceptualization, Data curation, Formal analysis, Methodology, Project administration, Software, Writing – review & editing

* E-mail: ffgh36@sina.com

Affiliations Hebei Keqi Biotechnology Co., Ltd, Shijiazhuang, China, Hebei Keqi Cancer Research Center, Shijiazhuang, China

https://orcid.org/0009-0006-0237-4163

⨯
Yiyang Lei,

Roles Software, Validation, Writing – original draft

Affiliations Hebei Keqi Biotechnology Co., Ltd, Shijiazhuang, China, Hebei Keqi Cancer Research Center, Shijiazhuang, China
⨯
Zixuan Liu,

Roles Software, Visualization, Writing – original draft

Affiliation Hebei Keqi Biotechnology Co., Ltd, Shijiazhuang, China
⨯
Jiale Han

Roles Software, Validation

Affiliation Hebei Keqi Biotechnology Co., Ltd, Shijiazhuang, China
⨯

Integrative GWAS and RNA-Seq analysis for target identification and virtual drug screening in colorectal cancer

Qinghui Liu,
Yiyang Lei,
Zixuan Liu,
Jiale Han

x

Published: October 27, 2025
https://doi.org/10.1371/journal.pone.0333179

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Colorectal cancer
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Genome-wide association studies
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Gene expression
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Drug screening
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Long non-coding RNA
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Protein structure databases
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Cancer treatment
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Survival analysis
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