Global burden of polycystic ovary syndrome in women of reproductive age, 1990–2021: Analysis of the global burden of disease study 2021 with projections to 2050

Xinkuo Zheng; Meishen Liu; Zhaohui Bai; Ling Wu; Lili Geng; Yun Shen; Jing Na; Haonan Qiu; Yalin Xi

doi:10.1371/journal.pone.0333000

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Open Access

Peer-reviewed

Research Article

Global burden of polycystic ovary syndrome in women of reproductive age, 1990–2021: Analysis of the global burden of disease study 2021 with projections to 2050

Xinkuo Zheng ,

Contributed equally to this work with: Xinkuo Zheng, Yalin Xi

Roles Conceptualization, Data curation, Formal analysis, Writing – review & editing

* E-mail: xinkuo1994@hotmail.com (XZ); yalinxi@163.com (YX)

Affiliation Department of Pharmacy, Central Hospital of Dalian University of Technology, Dalian, Liaoning, China

https://orcid.org/0000-0001-6680-902X

⨯
Meishen Liu,

Roles Data curation, Software

Affiliation Department of Pharmacy, The Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China
⨯
Zhaohui Bai,

Roles Data curation, Validation, Writing – original draft

Affiliation Department of Pharmacy Administration and Clinical Pharmacy, School of Pharmaceutical Sciences, Peking University, Beijing, China
⨯
Ling Wu,

Roles Investigation

Affiliation Department of Pharmacy, Central Hospital of Dalian University of Technology, Dalian, Liaoning, China
⨯
Lili Geng,

Roles Data curation

Affiliation Department of Infectious Diseases, Central Hospital of Dalian University of Technology, Dalian, Liaoning, China
⨯
Yun Shen,

Roles Data curation, Investigation

Affiliation Department of Infectious Diseases, Central Hospital of Dalian University of Technology, Dalian, Liaoning, China
⨯
Jing Na,

Roles Data curation, Methodology

Affiliation Department of Gynecology and Obstetrics, The Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China
⨯
Haonan Qiu,

Roles Methodology, Software

Affiliation Department of Colorectal Surgery, Liaoning Cancer Institute and Hospital, Shenyang, Liaoning, China
⨯
Yalin Xi

Contributed equally to this work with: Xinkuo Zheng, Yalin Xi

Roles Conceptualization, Investigation

* E-mail: xinkuo1994@hotmail.com (XZ); yalinxi@163.com (YX)

Affiliation Department of Pharmacy, Central Hospital of Dalian University of Technology, Dalian, Liaoning, China
⨯

Global burden of polycystic ovary syndrome in women of reproductive age, 1990–2021: Analysis of the global burden of disease study 2021 with projections to 2050

Xinkuo Zheng,
Meishen Liu,
Zhaohui Bai,
Ling Wu,
Lili Geng,
Yun Shen,
Jing Na,
Haonan Qiu,
Yalin Xi

Published: October 7, 2025
https://doi.org/10.1371/journal.pone.0333000

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