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Open Access

Peer-reviewed

Research Article

Inhibition of LncRNA Kcnq1ot1 suppresses hypoxia-induced pyroptosis of H9C2 cells by regulating miR-27b-3p

Yingjie Yang ,

Contributed equally to this work with: Yingjie Yang, Yanchun Ou

Roles Conceptualization, Formal analysis, Writing – original draft, Writing – review & editing

Affiliation Guilin Medical University Affiliated Hospital, Guilin, Guangxi, China
⨯
Yanchun Ou ,

Contributed equally to this work with: Yingjie Yang, Yanchun Ou

Roles Formal analysis, Writing – original draft, Writing – review & editing

Affiliation Guilin Medical University Affiliated Hospital, Guilin, Guangxi, China
⨯
Guanlian Mo,

Roles Data curation, Formal analysis, Investigation, Writing – original draft

Affiliation Guilin Medical University Affiliated Hospital, Guilin, Guangxi, China
⨯
Jing Wen,

Roles Data curation, Formal analysis, Investigation, Writing – original draft

Affiliation Guilin Medical University Affiliated Hospital, Guilin, Guangxi, China
⨯
Limin Liang,

Roles Data curation, Formal analysis, Investigation, Writing – original draft

Affiliation Guilin Medical University Affiliated Hospital, Guilin, Guangxi, China
⨯
Shirong Wang,

Roles Data curation, Formal analysis, Investigation, Writing – original draft

Affiliation Guilin Medical University Affiliated Hospital, Guilin, Guangxi, China
⨯
Jinyi Li

Roles Conceptualization, Investigation, Writing – review & editing

* E-mail: yzrcg@126.com

Affiliation Guilin Medical University Affiliated Hospital, Guilin, Guangxi, China

https://orcid.org/0009-0004-5414-8358

⨯

Inhibition of LncRNA Kcnq1ot1 suppresses hypoxia-induced pyroptosis of H9C2 cells by regulating miR-27b-3p

Yingjie Yang,
Yanchun Ou,
Guanlian Mo,
Jing Wen,
Limin Liang,
Shirong Wang,
Jinyi Li

x

Published: September 18, 2025
https://doi.org/10.1371/journal.pone.0332892

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Heart failure
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Inflammation
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Long non-coding RNA
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Cell binding assay
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Signal inhibition
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Cardiomyocytes
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