Identification of coexisting Mfrp^rd6 and Pde6b^rd10 mutations causing spontaneous retinal detachment in commercially available rd6 mice

• Asaka Lee Shiozawa ,

  Contributed equally to this work with: Asaka Lee Shiozawa, Tsutomu Igarashi

  Roles Conceptualization, Data curation, Investigation, Writing – original draft

  Affiliations Department of Ophthalmology, Nippon Medical School, Sendagi, Bunkyo-ku, Tokyo, Japan, Laboratory of Molecular Analysis, Nippon Medical School, Sendagi, Bunkyo-ku, Tokyo, Japan

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• Maika Hosoi Kobayashi,

  Roles Data curation, Project administration

  Affiliation Department of Ophthalmology, Nippon Medical School, Sendagi, Bunkyo-ku, Tokyo, Japan

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• Yusuke Shiozawa,

  Roles Data curation, Formal analysis

  Affiliation Laboratory of Molecular Analysis, Nippon Medical School, Sendagi, Bunkyo-ku, Tokyo, Japan

  https://orcid.org/0000-0001-8673-677X

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• Yasuhiro Ikeda,

  Roles Formal analysis, Writing – review & editing

  Affiliation Faculty of Medicine, University of Miyazaki, Kihara, Kiyotake, Miyazaki City, Miyazaki, Japan

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• Yoshitaka Miyagawa,

  Roles Data curation, Project administration, Writing – review & editing

  Affiliation Department of Biochemistry and Molecular Biology, Nippon Medical School, Sendagi, Bunkyo-ku, Tokyo, Japan

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• Fumiki Okamoto,

  Roles Formal analysis, Writing – review & editing

  Affiliation Department of Ophthalmology, Nippon Medical School, Sendagi, Bunkyo-ku, Tokyo, Japan

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• Mashito Sakai,

  Roles Formal analysis, Supervision, Writing – review & editing

  Affiliation Department of Biochemistry and Molecular Biology, Nippon Medical School, Sendagi, Bunkyo-ku, Tokyo, Japan

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• Takashi Okada,

  Roles Formal analysis, Funding acquisition, Writing – review & editing

  Affiliation Division of Molecular and Medical Genetics, Center for Gene and Cell Therapy, Institute of Medical Science, University of Tokyo, Shirokanedai, Minato-ku, Tokyo, Japan

  https://orcid.org/0000-0002-2910-3797

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• Tsutomu Igarashi

  Contributed equally to this work with: Asaka Lee Shiozawa, Tsutomu Igarashi

  Roles Conceptualization, Data curation, Funding acquisition, Writing – original draft, Writing – review & editing

  * E-mail: tutomu@nms.ac.jp

  Affiliations Department of Biochemistry and Molecular Biology, Nippon Medical School, Sendagi, Bunkyo-ku, Tokyo, Japan, Department of Ophthalmology, Nippon Medical School Chiba Hokusoh Hospital, Kamakari, Inzai City, Chiba, Japan

  https://orcid.org/0000-0002-7467-6746

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