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Open Access

Peer-reviewed

Research Article

A blueprint of synergistic effect in Crataegus pinnatifida and obesity-related gut microbiota against obesity via systems biology concept

Jinghui Xie,

Roles Conceptualization, Methodology, Writing – original draft

Affiliation School of Basic Medical Sciences, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, PR China
⨯
Haofang Guan,

Roles Data curation, Writing – original draft

Affiliation School of Basic Medical Sciences, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, PR China
⨯
Maohui Liu,

Roles Visualization, Writing – original draft

Affiliation School of Basic Medical Sciences, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, PR China
⨯
Weijun Ding

Roles Conceptualization, Data curation, Methodology, Supervision, Visualization, Writing – original draft, Writing – review & editing

* E-mail: Dingweijun@cdutcm.edu.cn

Affiliation School of Basic Medical Sciences, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, PR China

https://orcid.org/0000-0002-4933-7347

⨯

A blueprint of synergistic effect in Crataegus pinnatifida and obesity-related gut microbiota against obesity via systems biology concept

Jinghui Xie,
Haofang Guan,
Maohui Liu,
Weijun Ding

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Published: October 1, 2025
https://doi.org/10.1371/journal.pone.0332038

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Obesity
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Gut bacteria
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Pharmacology
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Bioinformatics
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Gene expression
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Genetic networks
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MAPK signaling cascades
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