Preliminary study on metabolite differences between two obesity syndromes based on Q Exactive liquid chromatography–tandem mass spectrometry metabolomics

Ye Jing; Xiaoxuan Xu; Yanhong Wang; Xue Qu; Yunlong Guo; Ao Guo; Yulin Dai; Yangyang Liu; Hao Yue

doi:10.1371/journal.pone.0331901

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Open Access

Peer-reviewed

Research Article

Preliminary study on metabolite differences between two obesity syndromes based on Q Exactive liquid chromatography–tandem mass spectrometry metabolomics

Ye Jing ,

Roles Data curation, Investigation, Software, Writing – review & editing

¶☯ YJ and XX contribute equally to this study.

Affiliation Jilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun, China
⨯
Xiaoxuan Xu ,

Roles Data curation, Investigation, Software, Writing – review & editing

¶☯ YJ and XX contribute equally to this study.

Affiliation Department of College of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun, China
⨯
Yanhong Wang,

Roles Formal analysis, Investigation, Software, Writing – original draft

Affiliation Changchun University of Chinese Medicine, Changchun, China
⨯
Xue Qu,

Roles Data curation, Formal analysis, Validation, Visualization

Affiliation Department of College of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun, China
⨯
Yunlong Guo,

Roles Investigation, Methodology

Affiliation Jilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun, China
⨯
Ao Guo,

Roles Data curation, Formal analysis, Validation, Visualization

Affiliation Jilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun, China
⨯
Yulin Dai ,

Roles Conceptualization, Funding acquisition, Project administration, Resources

* E-mail: daiyl@ccucm.edu.cn (YLD), 996439299@qq.com (YYL)

Affiliation Jilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun, China
⨯
Yangyang Liu ,

Roles Methodology, Resources, Supervision

* E-mail: daiyl@ccucm.edu.cn (YLD), 996439299@qq.com (YYL)

Affiliation Department of Prevention and treatment of disease Care Center, The Affiliated Hospital to Changchun University of Chinese Medicine, Changchun, China

https://orcid.org/0000-0002-3837-9066

⨯
Hao Yue

Roles Conceptualization, Funding acquisition, Project administration, Resources

Affiliation Jilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun, China
⨯

Preliminary study on metabolite differences between two obesity syndromes based on Q Exactive liquid chromatography–tandem mass spectrometry metabolomics

Ye Jing,
Xiaoxuan Xu,
Yanhong Wang,
Xue Qu,
Yunlong Guo,
Ao Guo,
Yulin Dai,
Yangyang Liu,
Hao Yue

Published: September 10, 2025
https://doi.org/10.1371/journal.pone.0331901

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Metabolites
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