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Open Access

Peer-reviewed

Research Article

KYLO-0603, a novel liver-targeting, thyroid hormone receptor-β agonist for the inhibition of MASH progression

Xueqin lu,

Roles Investigation

Affiliation Kylonova (Xiamen) biopharma Co., Ltd, Xiamen, China
⨯
Shengjun Wang,

Roles Investigation

Affiliation Kylonova (Xiamen) biopharma Co., Ltd, Xiamen, China
⨯
Yanchun Du,

Roles Investigation

Affiliation Kylonova (Xiamen) biopharma Co., Ltd, Xiamen, China
⨯
Bixian Xie,

Roles Investigation

Affiliation Kylonova (Xiamen) biopharma Co., Ltd, Xiamen, China
⨯
Qingyan Chen,

Roles Investigation

Affiliation Kylonova (Xiamen) biopharma Co., Ltd, Xiamen, China
⨯
Jinzhen Lin,

Roles Investigation

Affiliation Kylonova (Xiamen) biopharma Co., Ltd, Xiamen, China
⨯
Bailing Chen,

Roles Investigation, Writing – original draft, Writing – review & editing

Affiliations Kylonova (Xiamen) biopharma Co., Ltd, Xiamen, China, Hygieia pharmaceuticals Co., Ltd, Hangzhou, China
⨯
Kunyuan Cui

Roles Data curation, Investigation, Methodology, Writing – review & editing

* E-mail: cuiky@hygieiapharma.com

Affiliations Kylonova (Xiamen) biopharma Co., Ltd, Xiamen, China, Hygieia pharmaceuticals Co., Ltd, Hangzhou, China
⨯

KYLO-0603, a novel liver-targeting, thyroid hormone receptor-β agonist for the inhibition of MASH progression

Xueqin lu,
Shengjun Wang,
Yanchun Du,
Bixian Xie,
Qingyan Chen,
Jinzhen Lin,
Bailing Chen,
Kunyuan Cui

x

Published: September 15, 2025
https://doi.org/10.1371/journal.pone.0331768

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