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Open Access

Peer-reviewed

Research Article

Determining minimal inhibitory concentrations and antibiotic susceptibility for Enterobacterales by flow cytometry using reactive oxygen species as a marker

Jia Hao Yeo,

Roles Conceptualization, Data curation, Investigation, Visualization, Writing – original draft

Affiliations Division of Pharmacy, Singapore General Hospital, Singapore, SingHealth-Duke-NUS Academic Clinical Programme, Singapore

https://orcid.org/0000-0001-6478-5888

⨯
Nasren Begam,

Roles Investigation, Project administration

Affiliation Division of Pharmacy, Singapore General Hospital, Singapore
⨯
Wan Ting Leow,

Roles Methodology, Project administration

Affiliation Division of Pharmacy, Singapore General Hospital, Singapore
⨯
Andrea Lay-Hoon Kwa

* E-mail: andrea.kwa.l.h@sgh.com.sg

Affiliations Division of Pharmacy, Singapore General Hospital, Singapore, SingHealth-Duke-NUS Academic Clinical Programme, Singapore, Department of Pharmacy, National University of Singapore, Singapore, Emerging Infection Diseases Program, Duke-NUS Graduate Medical School, Singapore
⨯

Determining minimal inhibitory concentrations and antibiotic susceptibility for Enterobacterales by flow cytometry using reactive oxygen species as a marker

Jia Hao Yeo,
Nasren Begam,
Wan Ting Leow,
Andrea Lay-Hoon Kwa

x

Published: September 4, 2025
https://doi.org/10.1371/journal.pone.0331217

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Antibiotics
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Flow cytometry
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Bacterial broth dilution
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Reactive oxygen species
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Escherichia coli
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Klebsiella pneumoniae
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Polymyxins
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Singapore
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