International Network of Antibiotic Allergy Nations (iNAAN): Protocol for a type 2 hybrid effectiveness-implementation multicentre prospective cohort and target trial emulation study evaluating penicillin allergy delabeling via direct oral challenge

• Elise A. Mitri ,

  Roles Conceptualization, Data curation, Methodology, Project administration, Writing – original draft, Writing – review & editing

  * E-mail: elise.mitri@austin.org.au

  Affiliations Department of Infectious Diseases, at the Peter Doherty Institute for Infection and Immunology, Melbourne Medical School, University of Melbourne, Melbourne, Victoria, Australia, Centre for Antibiotic Allergy and Research, Department of Infectious Diseases and Immunology, Austin Health, Melbourne, Victoria, Australia, National Allergy Centre of Excellence (NACE), Parkville, Victoria, Australia

  https://orcid.org/0000-0002-1250-2847

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• Luke R. Fletcher,

  Roles Data curation, Software, Writing – review & editing

  Affiliations Department of Anaesthesia, Austin Health, Melbourne, Victoria, Australia, Department of Critical Care, University of Melbourne, Melbourne, Victoria, Australia, Data Analytics Research and Evaluation (DARE) Centre, Austin Health, Melbourne, Victoria, Australia

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• Camille Paynter,

  Roles Conceptualization, Methodology, Writing – review & editing

  Affiliation School of Health Sciences, The University of Melbourne, Melbourne, Victoria, Australia

  https://orcid.org/0000-0002-1845-126X

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• Sara Vogrin,

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Writing – review & editing

  Affiliation Centre for Antibiotic Allergy and Research, Department of Infectious Diseases and Immunology, Austin Health, Melbourne, Victoria, Australia

  https://orcid.org/0000-0002-1597-9421

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• Fiona James,

  Roles Conceptualization, Project administration, Writing – review & editing

  Affiliation Centre for Antibiotic Allergy and Research, Department of Infectious Diseases and Immunology, Austin Health, Melbourne, Victoria, Australia

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• Irvin Ng,

  Roles Project administration, Writing – review & editing

  Affiliation Centre for Antibiotic Allergy and Research, Department of Infectious Diseases and Immunology, Austin Health, Melbourne, Victoria, Australia

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• Natasha E. Holmes,

  Roles Supervision, Writing – review & editing

  Affiliations Department of Infectious Diseases, at the Peter Doherty Institute for Infection and Immunology, Melbourne Medical School, University of Melbourne, Melbourne, Victoria, Australia, Centre for Antibiotic Allergy and Research, Department of Infectious Diseases and Immunology, Austin Health, Melbourne, Victoria, Australia

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• Courtney Ierano,

  Roles Supervision, Writing – review & editing

  Affiliations Department of Infectious Diseases, at the Peter Doherty Institute for Infection and Immunology, Melbourne Medical School, University of Melbourne, Melbourne, Victoria, Australia, National Centre for Antimicrobial Stewardship, Department of Infectious Diseases, University of Melbourne, Melbourne, Victoria, Australia

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• Jason A. Roberts,

  Roles Supervision, Writing – review & editing

  Affiliations University of Queensland Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Brisbane, Queensland, Australia, Herston Infectious Diseases Institute (HeIDI), Metro North Health, Brisbane, Queensland, Australia, Departments of Pharmacy and Intensive Care Medicine, Royal Brisbane and Women’s Hospital, Brisbane, Queensland, Australia, UR UM 103, University of Montpellier, Division of Anesthesia Critical Care and Emergency and Pain Medicine, Nimes University Hospital, Nimes, France

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• Suran L. Fernando,

  Roles Supervision, Writing – review & editing

  Affiliations Department of Clinical Immunology and Allergy, Royal North Shore Hospital, St Leonards, New South Wales, Australia, Faculty of Medicine and Health, University of Sydney, Camperdown, New South Wales, Australia

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• Marlena Klaic,

  Roles Conceptualization, Methodology, Writing – review & editing

  Affiliation School of Health Sciences, The University of Melbourne, Melbourne, Victoria, Australia

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• Jason A. Trubiano

  Roles Conceptualization, Data curation, Methodology, Supervision, Writing – original draft, Writing – review & editing

  Affiliations Department of Infectious Diseases, at the Peter Doherty Institute for Infection and Immunology, Melbourne Medical School, University of Melbourne, Melbourne, Victoria, Australia, Centre for Antibiotic Allergy and Research, Department of Infectious Diseases and Immunology, Austin Health, Melbourne, Victoria, Australia, National Allergy Centre of Excellence (NACE), Parkville, Victoria, Australia

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