Dosimetry study of 3D-printed noncoplanar template-assisted CT-guided 125I seed implantation for the treatment of recurrent and metastatic tumors in the head and neck

Lingyun Qiu; Rong Wu; Yinan Chen; Haixin Xiang; Wenming Zhan; Yinghao Zhang; Qiang Li; Huaxin Liu; Jieni Ding; Yucheng Li; Aihong Bi; Limin Luo; Yongshi Jia; Weijun Chen; Kainan Shao

doi:10.1371/journal.pone.0330271

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Open Access

Peer-reviewed

Research Article

Dosimetry study of 3D-printed noncoplanar template-assisted CT-guided ¹²⁵I seed implantation for the treatment of recurrent and metastatic tumors in the head and neck

Lingyun Qiu,

Roles Writing – original draft

Affiliation Cancer Center, Department of Radiation Oncology, Zhejiang Provincial People’s Hospital, Affiliated People’s Hospital, Hangzhou Medical College, Hangzhou, Zhejiang, China

https://orcid.org/0009-0007-5974-1689

⨯
Rong Wu,

Roles Conceptualization

Affiliation Department of Breast Surgery, Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou Hospital of Traditional Chinese Medicine, Hangzhou, Zhejiang, China.,
⨯
Yinan Chen,

Roles Software

Affiliation School of Medical Technology, Yunnan Engineering Vocational College, Yunnan, China
⨯
Haixin Xiang,

Roles Data curation

Affiliation Radiotherapy and Chemotherapy Center, First Affiliated Hospital of Ningbo University, Ningbo, China
⨯
Wenming Zhan,

Roles Conceptualization

Affiliation Cancer Center, Department of Radiation Oncology, Zhejiang Provincial People’s Hospital, Affiliated People’s Hospital, Hangzhou Medical College, Hangzhou, Zhejiang, China
⨯
Yinghao Zhang,

Roles Formal analysis

Affiliation Cancer Center, Department of Radiation Oncology, Zhejiang Provincial People’s Hospital, Affiliated People’s Hospital, Hangzhou Medical College, Hangzhou, Zhejiang, China
⨯
Qiang Li,

Roles Funding acquisition

Affiliation Cancer Center, Department of Radiation Oncology, Zhejiang Provincial People’s Hospital, Affiliated People’s Hospital, Hangzhou Medical College, Hangzhou, Zhejiang, China
⨯
Huaxin Liu,

Roles Investigation

Affiliation Cancer Center, Department of Radiation Oncology, Zhejiang Provincial People’s Hospital, Affiliated People’s Hospital, Hangzhou Medical College, Hangzhou, Zhejiang, China
⨯
Jieni Ding,

Roles Methodology

Affiliation Cancer Center, Department of Radiation Oncology, Zhejiang Provincial People’s Hospital, Affiliated People’s Hospital, Hangzhou Medical College, Hangzhou, Zhejiang, China
⨯
Yucheng Li,

Roles Resources

Affiliation Cancer Center, Department of Radiation Oncology, Zhejiang Provincial People’s Hospital, Affiliated People’s Hospital, Hangzhou Medical College, Hangzhou, Zhejiang, China
⨯
Aihong Bi,

Roles Supervision

Affiliation Cancer Center, Department of Radiation Oncology, Zhejiang Provincial People’s Hospital, Affiliated People’s Hospital, Hangzhou Medical College, Hangzhou, Zhejiang, China
⨯
Limin Luo,

Roles Visualization

Affiliation Cancer Center, Department of Radiation Oncology, Zhejiang Provincial People’s Hospital, Affiliated People’s Hospital, Hangzhou Medical College, Hangzhou, Zhejiang, China
⨯
Yongshi Jia,

Roles Supervision

Affiliation Cancer Center, Department of Radiation Oncology, Zhejiang Provincial People’s Hospital, Affiliated People’s Hospital, Hangzhou Medical College, Hangzhou, Zhejiang, China
⨯
Weijun Chen,

Roles Project administration

Affiliation Cancer Center, Department of Radiation Oncology, Zhejiang Provincial People’s Hospital, Affiliated People’s Hospital, Hangzhou Medical College, Hangzhou, Zhejiang, China
⨯
Kainan Shao

Roles Writing – review & editing

* E-mail: shaokainan@hmc.edu.cn

Affiliation Cancer Center, Department of Radiation Oncology, Zhejiang Provincial People’s Hospital, Affiliated People’s Hospital, Hangzhou Medical College, Hangzhou, Zhejiang, China

https://orcid.org/0009-0001-2186-5455

⨯

Dosimetry study of 3D-printed noncoplanar template-assisted CT-guided ¹²⁵I seed implantation for the treatment of recurrent and metastatic tumors in the head and neck

Lingyun Qiu,
Rong Wu,
Yinan Chen,
Haixin Xiang,
Wenming Zhan,
Yinghao Zhang,
Qiang Li,
Huaxin Liu,
Jieni Ding,
Yucheng Li

Published: August 14, 2025
https://doi.org/10.1371/journal.pone.0330271

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Medical implants
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Head and neck cancers
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