Evaluating the potential effect of PCSK9 inhibitors on the risk of sudden cardiac death and ventricular arrhythmias: A meta-analysis of randomized controlled trials

Lei Zhang; Yuan-Yuan Li; Xue-Hui Liu; Hong-Jun Liu; Qiang Xu

doi:10.1371/journal.pone.0329676

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Open Access

Peer-reviewed

Research Article

Evaluating the potential effect of PCSK9 inhibitors on the risk of sudden cardiac death and ventricular arrhythmias: A meta-analysis of randomized controlled trials

Lei Zhang ,

Contributed equally to this work with: Lei Zhang, Yuan-Yuan Li

Roles Conceptualization, Data curation, Formal analysis, Methodology, Software, Writing – original draft

Affiliations Department of Cardiology, Yichang Hospital of Traditional Chinese Medicine, Yichang, China, Traditional Chinese Medicine Hospital of China Three Gorges University, China Three Gorges University, Yichang, China
⨯
Yuan-Yuan Li ,

Contributed equally to this work with: Lei Zhang, Yuan-Yuan Li

Roles Conceptualization, Data curation, Formal analysis, Methodology, Software

Affiliation Chengdong Community Service Center of Wujiagang District, Yichang, China
⨯
Xue-Hui Liu,

Roles Conceptualization, Data curation, Methodology

Affiliations Department of Cardiology, Yichang Hospital of Traditional Chinese Medicine, Yichang, China, Traditional Chinese Medicine Hospital of China Three Gorges University, China Three Gorges University, Yichang, China
⨯
Hong-Jun Liu,

Roles Conceptualization

Affiliations Department of Cardiology, Yichang Hospital of Traditional Chinese Medicine, Yichang, China, Traditional Chinese Medicine Hospital of China Three Gorges University, China Three Gorges University, Yichang, China
⨯
Qiang Xu

Roles Conceptualization, Supervision, Writing – review & editing

* E-mail: yczyyxq@sina.com

Affiliations Department of Cardiology, Yichang Hospital of Traditional Chinese Medicine, Yichang, China, Traditional Chinese Medicine Hospital of China Three Gorges University, China Three Gorges University, Yichang, China

https://orcid.org/0000-0002-1536-0565

⨯

Evaluating the potential effect of PCSK9 inhibitors on the risk of sudden cardiac death and ventricular arrhythmias: A meta-analysis of randomized controlled trials

Lei Zhang,
Yuan-Yuan Li,
Xue-Hui Liu,
Hong-Jun Liu,
Qiang Xu

Published: August 8, 2025
https://doi.org/10.1371/journal.pone.0329676

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