CRISPR/Cas9 mediated ENT2 gene knockout altered purine catabolic pathway and induced apoptosis in colorectal cell lines

• Safaa M. Naes,

  Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliations Department of Biochemistry and Molecular Medicine, Faculty of Medicine, Universiti Teknologi MARA, Cawangan Selangor, Kampus Sungai Buloh, Sungai Buloh, Selangor, Malaysia, Faculty of Medicine, Institute of Medical and Molecular Biotechnology, Universiti Teknologi MARA, Cawangan Selangor, Kampus Sungai Buloh, Sungai Buloh, Selangor, Malaysia, Faculty of Health and Life Sciences, Management and Science University, Shah Alam, Selangor, Malaysia

  https://orcid.org/0000-0002-5127-703X

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• Sharaniza Ab-Rahim,

  Roles Conceptualization, Supervision, Writing – review & editing

  Affiliation Department of Biochemistry and Molecular Medicine, Faculty of Medicine, Universiti Teknologi MARA, Cawangan Selangor, Kampus Sungai Buloh, Sungai Buloh, Selangor, Malaysia

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• Musalmah Mazlan,

  Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

  Affiliation Department of Biochemistry and Molecular Medicine, Faculty of Medicine, Universiti Teknologi MARA, Cawangan Selangor, Kampus Sungai Buloh, Sungai Buloh, Selangor, Malaysia

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• Saiful Effendi Syafruddin,

  Roles Data curation, Investigation, Writing – review & editing

  Affiliation UKM Medical Molecular Biology Institute, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia

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• M. Aiman Mohtar,

  Roles Investigation, Writing – review & editing

  Affiliation UKM Medical Molecular Biology Institute, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia

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• Asmaa Y. Abuhamad,

  Roles Data curation, Investigation, Writing – review & editing

  Affiliation Bionanotechnology Research Group and Department of Biochemistry, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, Seri Kembangan, Selangor, Malaysia

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• Amirah Abdul Rahman

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Supervision, Validation, Writing – review & editing

  * E-mail: amirahar@uitm.edu.my

  Affiliations Department of Biochemistry and Molecular Medicine, Faculty of Medicine, Universiti Teknologi MARA, Cawangan Selangor, Kampus Sungai Buloh, Sungai Buloh, Selangor, Malaysia, Faculty of Medicine, Institute of Medical and Molecular Biotechnology, Universiti Teknologi MARA, Cawangan Selangor, Kampus Sungai Buloh, Sungai Buloh, Selangor, Malaysia

  https://orcid.org/0000-0002-3566-1787

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