Computational elucidation of stomidazolone mediated inhibition of stomatal differentiation and its implication in plant developmental regulation

Syeda Sumayya Tariq; Urooj Qureshi; Mamona Mushtaq; Maria Nasim; Mohammad Nur-e-Alam; Tawfeq A. AlHowiriny; Yan Wang; Zaheer Ul-Haq

doi:10.1371/journal.pone.0329401

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Open Access

Peer-reviewed

Research Article

Computational elucidation of stomidazolone mediated inhibition of stomatal differentiation and its implication in plant developmental regulation

Syeda Sumayya Tariq ,

Contributed equally to this work with: Syeda Sumayya Tariq, Urooj Qureshi

Roles Investigation, Writing – original draft

Affiliation Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan
⨯
Urooj Qureshi ,

Contributed equally to this work with: Syeda Sumayya Tariq, Urooj Qureshi

Roles Investigation

Affiliation H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan
⨯
Mamona Mushtaq,

Roles Investigation

Affiliation Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan
⨯
Maria Nasim,

Roles Investigation

Affiliation Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan
⨯
Mohammad Nur-e-Alam,

Roles Writing – review & editing

Affiliation Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh, Kingdom of Saudi Arabia
⨯
Tawfeq A. AlHowiriny,

Roles Writing – review & editing

Affiliation Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh, Kingdom of Saudi Arabia
⨯
Yan Wang,

Roles Writing – review & editing

Affiliation State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences, Guangxi Normal University, Guilin, China
⨯
Zaheer Ul-Haq

Roles Resources, Supervision, Writing – review & editing

* E-mail: zaheer.qasmi@iccs.edu

Affiliation Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan

https://orcid.org/0000-0002-8530-8711

⨯

Computational elucidation of stomidazolone mediated inhibition of stomatal differentiation and its implication in plant developmental regulation

Syeda Sumayya Tariq,
Urooj Qureshi,
Mamona Mushtaq,
Maria Nasim,
Mohammad Nur-e-Alam,
Tawfeq A. AlHowiriny,
Yan Wang,
Zaheer Ul-Haq

Published: February 10, 2026
https://doi.org/10.1371/journal.pone.0329401

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