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Open Access
Peer-reviewed
Research Article
Integrative molecular network analysis of genetic risk factors to infer biomarkers and therapeutic targets for rheumatoid arthritis
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Sakhaa Alsaedi,
Roles Data curation, Formal analysis, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing
Affiliations Computer Science, Division of Computer, Electrical and Mathematical Sciences and Engineering (CEMSE), King Abdullah University of Science and Technology (KAUST), Thuwal, Saudi Arabia, Center of Excellence on Smart Health, King Abdullah University of Science and Technology (KAUST), Thuwal, Kingdom of Saudi Arabia, Center of Excellence for Generative AI, King Abdullah University of Science and Technology (KAUST), Thuwal, Kingdom of Saudi Arabia, College of Computer Science and Engineering (CCSE), Taibah University, Madinah, Saudi Arabia
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Katsuhiko Mineta,
Roles Writing – review & editing
Affiliations Research Organization for Nano & Life Innovation, Waseda University, Shinjuku, Tokyo, Japan, Department of System Engineering, Graduate School of Science and Engineering, Shizuoka Institute of Science and Technology, Aoi, Shizuoka, Japan, Marine Open Innovation Institute (MaOI), Shimizu, Shizuoka, Japan
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Naoto Tamura,
Roles Investigation, Validation
Affiliation Department of Internal Medicine and Rheumatology, Juntendo University, Tokyo, Japan
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Xin Gao,
Roles Supervision
Affiliations Computer Science, Division of Computer, Electrical and Mathematical Sciences and Engineering (CEMSE), King Abdullah University of Science and Technology (KAUST), Thuwal, Saudi Arabia, Center of Excellence on Smart Health, King Abdullah University of Science and Technology (KAUST), Thuwal, Kingdom of Saudi Arabia, Center of Excellence for Generative AI, King Abdullah University of Science and Technology (KAUST), Thuwal, Kingdom of Saudi Arabia
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Takashi Gojobori ,
Roles Supervision, Validation, Writing – review & editing
* E-mail: takashi.gojobori@kaust.edu.sa
Affiliations Center of Excellence on Smart Health, King Abdullah University of Science and Technology (KAUST), Thuwal, Kingdom of Saudi Arabia, Center of Excellence for Generative AI, King Abdullah University of Science and Technology (KAUST), Thuwal, Kingdom of Saudi Arabia, Biological and Environmental Sciences and Engineering, King Abdullah University of Science and Technology (KAUST), Thuwal, Saudi Arabia, Marine Open Innovation Institute (MaOI), Shizuoka, Japan, Department of Life Sciences, National Cheng Kung University, Tainan, Taiwan
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Michihiro Ogasawara
Roles Investigation, Validation, Writing – review & editing
Affiliation Biological and Environmental Sciences and Engineering, King Abdullah University of Science and Technology (KAUST), Thuwal, Saudi Arabia
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Integrative molecular network analysis of genetic risk factors to infer biomarkers and therapeutic targets for rheumatoid arthritis
- Sakhaa Alsaedi,
- Katsuhiko Mineta,
- Naoto Tamura,
- Xin Gao,
- Takashi Gojobori,
- Michihiro Ogasawara
- Published: August 21, 2025
- https://doi.org/10.1371/journal.pone.0329101