Effects of standard and low doses of estradiol on markers of endometrial receptivity in frozen-thawed embryo transfer cycles: Double-blind, randomized clinical trial

Nichamon Parkpinyo; Isarin Thanaboonyawat; Japarath Prechapanich; Pitak Laokirkkiat; Roungsin Choavaratana; Suchanan Hanamornroongruang; Somsin Petyim

doi:10.1371/journal.pone.0328871

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Open Access

Peer-reviewed

Research Article

Effects of standard and low doses of estradiol on markers of endometrial receptivity in frozen-thawed embryo transfer cycles: Double-blind, randomized clinical trial

Nichamon Parkpinyo,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Software, Writing – original draft, Writing – review & editing

Affiliation Reproductive Biology and Infertility Unit, Department of Obstetrics and Gynecology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
⨯
Isarin Thanaboonyawat,

Roles Investigation, Writing – review & editing

Affiliation Reproductive Biology and Infertility Unit, Department of Obstetrics and Gynecology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
⨯
Japarath Prechapanich,

Roles Investigation

Affiliation Reproductive Biology and Infertility Unit, Department of Obstetrics and Gynecology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
⨯
Pitak Laokirkkiat,

Roles Conceptualization, Supervision

Affiliation Reproductive Biology and Infertility Unit, Department of Obstetrics and Gynecology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
⨯
Roungsin Choavaratana,

Roles Conceptualization, Supervision

Affiliation Reproductive Biology and Infertility Unit, Department of Obstetrics and Gynecology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
⨯
Suchanan Hanamornroongruang,

Roles Conceptualization, Data curation, Methodology, Writing – original draft

Affiliation Department of Pathology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
⨯
Somsin Petyim

Roles Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Validation, Writing – original draft, Writing – review & editing

* E-mail: somsin101@yahoo.com

Affiliations Reproductive Biology and Infertility Unit, Department of Obstetrics and Gynecology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand, Center of Reproductive and Stem Cell Biology Unit, Department of Obstetrics and Gynecology y, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand

https://orcid.org/0000-0002-5577-6389

⨯

Effects of standard and low doses of estradiol on markers of endometrial receptivity in frozen-thawed embryo transfer cycles: Double-blind, randomized clinical trial

Nichamon Parkpinyo,
Isarin Thanaboonyawat,
Japarath Prechapanich,
Pitak Laokirkkiat,
Roungsin Choavaratana,
Suchanan Hanamornroongruang,
Somsin Petyim

Published: July 28, 2025
https://doi.org/10.1371/journal.pone.0328871

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Estradiol
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Integrins
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Endometrium
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Estrogens
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