Mechanistic investigation of glycolysis and pyroptosis in colon adenocarcinoma tissues, and prognostic analysis of patient clinical outcomes

Yongling Wang; Zan Yuan; Yi Lao; Jiangtao He; Shufen Mo; Kangbiao Chen; Yanyan Ye; Lu Huang

doi:10.1371/journal.pone.0328560

Loading metrics

Open Access

Peer-reviewed

Research Article

Mechanistic investigation of glycolysis and pyroptosis in colon adenocarcinoma tissues, and prognostic analysis of patient clinical outcomes

Yongling Wang,

Roles Data curation, Formal analysis, Methodology, Software, Validation, Writing – original draft

Affiliation The First Department of Medical Oncology, Central Hospital of Guangdong Provincial Nongken, Zhanjiang Cancer Hospital, Zhanjiang, China
⨯
Zan Yuan,

Roles Data curation, Resources, Software, Writing – original draft

Affiliations Guangdong Medical University, Zhanjiang, China, The Fourth Department of Medical Oncology, Central Hospital of Guangdong Provincial Nongken, Zhanjiang Cancer Hospital, Zhanjiang, China
⨯
Yi Lao,

Roles Data curation, Resources

Affiliation The Fourth Department of Medical Oncology, Central Hospital of Guangdong Provincial Nongken, Zhanjiang Cancer Hospital, Zhanjiang, China
⨯
Jiangtao He,

Roles Data curation, Resources

Affiliation The Second Department of Medical Oncology, Central Hospital of Guangdong Provincial Nongken, Zhanjiang Cancer Hospital, Zhanjiang, China
⨯
Shufen Mo,

Roles Data curation, Resources

Affiliation The Second Department of Medical Oncology, Central Hospital of Guangdong Provincial Nongken, Zhanjiang Cancer Hospital, Zhanjiang, China
⨯
Kangbiao Chen,

Roles Data curation, Resources

Affiliation The Fourth Department of Medical Oncology, Central Hospital of Guangdong Provincial Nongken, Zhanjiang Cancer Hospital, Zhanjiang, China
⨯
Yanyan Ye,

Roles Data curation, Resources

Affiliation The Fourth Department of Medical Oncology, Central Hospital of Guangdong Provincial Nongken, Zhanjiang Cancer Hospital, Zhanjiang, China
⨯
Lu Huang

Roles Methodology, Project administration, Supervision, Writing – review & editing

* E-mail: luternh@163.com

Affiliation The Fourth Department of Medical Oncology, Central Hospital of Guangdong Provincial Nongken, Zhanjiang Cancer Hospital, Zhanjiang, China

https://orcid.org/0000-0002-4145-4717

⨯

Mechanistic investigation of glycolysis and pyroptosis in colon adenocarcinoma tissues, and prognostic analysis of patient clinical outcomes

Yongling Wang,
Zan Yuan,
Yi Lao,
Jiangtao He,
Shufen Mo,
Kangbiao Chen,
Yanyan Ye,
Lu Huang

Published: July 18, 2025
https://doi.org/10.1371/journal.pone.0328560

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Gene expression
Is the Subject Area "Gene expression" applicable to this article?

Thanks for your feedback.
Cancer risk factors
Is the Subject Area "Cancer risk factors" applicable to this article?

Thanks for your feedback.
Glycolysis
Is the Subject Area "Glycolysis" applicable to this article?

Thanks for your feedback.
Colon adenocarcinoma
Is the Subject Area "Colon adenocarcinoma" applicable to this article?

Thanks for your feedback.
Cancers and neoplasms
Is the Subject Area "Cancers and neoplasms" applicable to this article?

Thanks for your feedback.
Genome analysis
Is the Subject Area "Genome analysis" applicable to this article?

Thanks for your feedback.
Gene ontologies
Is the Subject Area "Gene ontologies" applicable to this article?

Thanks for your feedback.
Medical risk factors
Is the Subject Area "Medical risk factors" applicable to this article?

Thanks for your feedback.