Targeted modulation of MMP9 and GRP78 via molecular interaction and in silico profiling of Curcuma caesia rhizome metabolites: A computational drug discovery approach for cancer therapy

• Mahek Desai ,

  Contributed equally to this work with: Mahek Desai, Soham Bhattacharya

  Roles Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft

  Affiliation Department of Life Sciences, Parul Institute of Applied Sciences, Parul University, Waghodia, Vadodara, Gujarat, India

  https://orcid.org/0009-0008-1400-9969

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• Soham Bhattacharya ,

  Contributed equally to this work with: Mahek Desai, Soham Bhattacharya

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Visualization, Writing – original draft

  * E-mail: bhattacharya@af.czu.cz

  Affiliation Department of Agroecology and Crop Production, Faculty of Agrobiology, Food and Natural Resources, Czech University of Life Sciences Prague, Suchdol, Czech Republic

  https://orcid.org/0000-0001-5998-4751

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• Saurabhkumar Mehta,

  Roles Formal analysis, Supervision, Writing – review & editing

  Affiliation Department of Life Sciences, Parul Institute of Applied Sciences, Parul University, Waghodia, Vadodara, Gujarat, India

  https://orcid.org/0009-0007-6645-1962

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• Kaushiki Joshi,

  Roles Data curation, Formal analysis, Investigation, Writing – review & editing

  Affiliation Department of Life Sciences, Parul Institute of Applied Sciences, Parul University, Waghodia, Vadodara, Gujarat, India

  https://orcid.org/0009-0002-3853-3438

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• Mitesh B. Solanki,

  Roles Formal analysis, Supervision, Writing – review & editing

  Affiliation Department of Physics, Parul Institute of Applied Sciences, Parul University, Waghodia, Vadodara, Gujarat, India

  https://orcid.org/0000-0002-4019-0203

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• Trilok Akhani,

  Roles Formal analysis, Writing – review & editing

  Affiliation Department of Physics, Parul Institute of Applied Sciences, Parul University, Waghodia, Vadodara, Gujarat, India

  https://orcid.org/0000-0002-3489-1708

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• Iva Viehmannová,

  Roles Formal analysis, Funding acquisition, Writing – review & editing

  Affiliation Department of Crop Sciences and Agroforestry, Faculty of Tropical AgriSciences, Czech University of Life Sciences Prague, Suchdol, Czech Republic

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• Eloy Fernández Cusimamani

  Roles Formal analysis, Funding acquisition, Writing – review & editing

  Affiliation Department of Crop Sciences and Agroforestry, Faculty of Tropical AgriSciences, Czech University of Life Sciences Prague, Suchdol, Czech Republic

  https://orcid.org/0000-0001-7835-9310

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