Core outcome sets in symptomatic peripheral artery disease, COS-PAD: Study protocol for developing core outcome sets in symptomatic PAD utilising systematic reviews, interviews, and delphi consensus

Akam Shwan; Maria Gonzalez-Aguado; Rob D. Sayers; John S.M. Houghton

doi:10.1371/journal.pone.0328453

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Core outcome sets in symptomatic peripheral artery disease, COS-PAD: Study protocol for developing core outcome sets in symptomatic PAD utilising systematic reviews, interviews, and delphi consensus

Akam Shwan ,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft

* E-mail: akam.shwan@nhs.net, as1610@leicester.ac.uk

Affiliations Department of Cardiovascular Sciences, University of Leicester, Leicester, United Kingdom, Leicester Vascular Institute, University Hospitals of Leicester NHS Trust, Leicester, United Kingdom, National Institute for Health and Care Research Leicester Biomedical Research Centre – The Glenfield Hospital, Leicester, United Kingdom

https://orcid.org/0009-0006-8051-8302

⨯
Maria Gonzalez-Aguado,

Roles Formal analysis, Methodology, Supervision, Validation, Writing – review & editing

Affiliation Department of Cardiovascular Sciences, University of Leicester, Leicester, United Kingdom
⨯
Rob D. Sayers,

Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Project administration, Resources, Software, Supervision, Validation, Writing – review & editing

Affiliations Department of Cardiovascular Sciences, University of Leicester, Leicester, United Kingdom, Leicester Vascular Institute, University Hospitals of Leicester NHS Trust, Leicester, United Kingdom, National Institute for Health and Care Research Leicester Biomedical Research Centre – The Glenfield Hospital, Leicester, United Kingdom
⨯
John S.M. Houghton

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Supervision, Validation, Writing – review & editing

Affiliations Department of Cardiovascular Sciences, University of Leicester, Leicester, United Kingdom, Leicester Vascular Institute, University Hospitals of Leicester NHS Trust, Leicester, United Kingdom, National Institute for Health and Care Research Leicester Biomedical Research Centre – The Glenfield Hospital, Leicester, United Kingdom
⨯

Core outcome sets in symptomatic peripheral artery disease, COS-PAD: Study protocol for developing core outcome sets in symptomatic PAD utilising systematic reviews, interviews, and delphi consensus

Akam Shwan,
Maria Gonzalez-Aguado,
Rob D. Sayers,
John S.M. Houghton

Published: July 17, 2025
https://doi.org/10.1371/journal.pone.0328453

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