Global, regional, and national burden of early-onset OA attributable to high BMI: 1990–2021 estimates and 2036 projections from the global burden of disease study

Binbin Zhang; Bin Dou; Wenzuo Gu; Chuan Lu; Qi Yan; Dawa Zhaxi; Yu Wang; Jiale Xu; Kewen Li

doi:10.1371/journal.pone.0328414

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Open Access

Peer-reviewed

Research Article

Global, regional, and national burden of early-onset OA attributable to high BMI: 1990–2021 estimates and 2036 projections from the global burden of disease study

Binbin Zhang ,

Contributed equally to this work with: Binbin Zhang, Bin Dou

Roles Data curation, Methodology, Software, Writing – original draft, Writing – review & editing

Affiliation Qinghai University Affiliated Hospital (The Clinical Medical School), Qinghai University, Xining, Qinghai, China
⨯
Bin Dou ,

Contributed equally to this work with: Binbin Zhang, Bin Dou

Roles Formal analysis, Writing – original draft, Writing – review & editing

Affiliation Qinghai University Affiliated Hospital (The Clinical Medical School), Qinghai University, Xining, Qinghai, China
⨯
Wenzuo Gu,

Roles Funding acquisition, Writing – review & editing

Affiliation Qinghai University Affiliated Hospital (The Clinical Medical School), Qinghai University, Xining, Qinghai, China
⨯
Chuan Lu,

Roles Formal analysis, Methodology, Software

Affiliation Qinghai University Affiliated Hospital (The Clinical Medical School), Qinghai University, Xining, Qinghai, China
⨯
Qi Yan,

Roles Data curation, Methodology, Software

Affiliation Qinghai University Affiliated Hospital (The Clinical Medical School), Qinghai University, Xining, Qinghai, China
⨯
Dawa Zhaxi,

Roles Formal analysis, Software

Affiliation Qinghai University Affiliated Hospital (The Clinical Medical School), Qinghai University, Xining, Qinghai, China
⨯
Yu Wang,

Roles Formal analysis, Software

Affiliation Qinghai University Affiliated Hospital (The Clinical Medical School), Qinghai University, Xining, Qinghai, China
⨯
Jiale Xu,

Roles Formal analysis, Software

Affiliation Qinghai University Affiliated Hospital (The Clinical Medical School), Qinghai University, Xining, Qinghai, China
⨯
Kewen Li

Roles Methodology, Software, Supervision, Writing – original draft, Writing – review & editing

* E-mail: qdfykwl@126.com

Affiliation Qinghai University Affiliated Hospital (The Clinical Medical School), Qinghai University, Xining, Qinghai, China

https://orcid.org/0000-0001-7950-2537

⨯

Global, regional, and national burden of early-onset OA attributable to high BMI: 1990–2021 estimates and 2036 projections from the global burden of disease study

Binbin Zhang,
Bin Dou,
Wenzuo Gu,
Chuan Lu,
Qi Yan,
Dawa Zhaxi,
Yu Wang,
Jiale Xu,
Kewen Li

Published: July 16, 2025
https://doi.org/10.1371/journal.pone.0328414

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