Single cell transcriptomic analysis reveals transcriptome differences of different cells between eosinophilic chronic rhinosinusitis with nasal polyps and non-eosinophilic chronic rhinosinusitis with nasal polyps

Ying Jin; Yuanshan Liang; Zhijun Wang; Yiting Jiang; Fayang Yuan; Tian Zhang

doi:10.1371/journal.pone.0328241

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Open Access

Peer-reviewed

Research Article

Single cell transcriptomic analysis reveals transcriptome differences of different cells between eosinophilic chronic rhinosinusitis with nasal polyps and non-eosinophilic chronic rhinosinusitis with nasal polyps

Ying Jin ,

Contributed equally to this work with: Ying Jin, Yuanshan Liang

Roles Conceptualization, Data curation, Formal analysis, Methodology, Writing – original draft

Affiliation Department of Otorhinolaryngology Head and Neck Surgery, Affiliated Hospital of Guizhou Medical University, Guiyang, China
⨯
Yuanshan Liang ,

Contributed equally to this work with: Ying Jin, Yuanshan Liang

Roles Conceptualization, Formal analysis, Software, Writing – original draft

Affiliation Department of Otorhinolaryngology Head and Neck Surgery, Affiliated Hospital of Guizhou Medical University, Guiyang, China
⨯
Zhijun Wang,

Roles Methodology, Project administration, Resources, Software

Affiliation Department of Otorhinolaryngology Head and Neck Surgery, Affiliated Hospital of Guizhou Medical University, Guiyang, China
⨯
Yiting Jiang,

Roles Methodology, Project administration, Software, Supervision

Affiliation Department of Otorhinolaryngology Head and Neck Surgery, Affiliated Hospital of Guizhou Medical University, Guiyang, China
⨯
Fayang Yuan,

Roles Data curation, Resources, Software

Affiliation Department of Otorhinolaryngology Head and Neck Surgery, Affiliated Hospital of Guizhou Medical University, Guiyang, China
⨯
Tian Zhang

Roles Conceptualization, Funding acquisition, Project administration, Writing – review & editing

* E-mail: entzhangtian@126.com

Affiliation Department of Otorhinolaryngology Head and Neck Surgery, Affiliated Hospital of Guizhou Medical University, Guiyang, China

https://orcid.org/0009-0003-1150-3842

⨯

Single cell transcriptomic analysis reveals transcriptome differences of different cells between eosinophilic chronic rhinosinusitis with nasal polyps and non-eosinophilic chronic rhinosinusitis with nasal polyps

Ying Jin,
Yuanshan Liang,
Zhijun Wang,
Yiting Jiang,
Fayang Yuan,
Tian Zhang

Published: July 28, 2025
https://doi.org/10.1371/journal.pone.0328241

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