Whole genome DNA methylation patterns in tissue and cfDNA associated with fibrosis reflect the complex signature of MASLD

• Jongseong Ahn ,

  Contributed equally to this work with: Jongseong Ahn, Soyeon Kim, Jae Yoon Jeong

  Roles Data curation, Formal analysis, Investigation, Methodology

  Affiliation IMBdx, Seoul, Republic of Korea

  ⨯
• Soyeon Kim ,

  Contributed equally to this work with: Jongseong Ahn, Soyeon Kim, Jae Yoon Jeong

  Roles Formal analysis, Methodology

  Affiliations Department of Pharmacy, College of Pharmacy, Seoul National University, Seoul, Republic of Korea, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, Republic of Korea

  ⨯
• Jae Yoon Jeong ,

  Contributed equally to this work with: Jongseong Ahn, Soyeon Kim, Jae Yoon Jeong

  Roles Resources

  Affiliation Department of Internal Medicine, Ewha Womans University College of Medicine, Division of Gastroenterology and Hepatology, Ewha Womans University Mokdong Hospital, Seoul, Republic of Korea

  ⨯
• Sunghoon Heo,

  Roles Methodology, Software

  Affiliation IMBdx, Seoul, Republic of Korea

  ⨯
• Kyung-hee Pyo,

  Roles Methodology

  Affiliations Department of Pharmacy, College of Pharmacy, Seoul National University, Seoul, Republic of Korea, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, Republic of Korea

  ⨯
• Eun-Ae Shin,

  Roles Methodology

  Affiliations Department of Pharmacy, College of Pharmacy, Seoul National University, Seoul, Republic of Korea, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, Republic of Korea

  ⨯
• Wonsik Kim,

  Roles Methodology

  Affiliations Department of Pharmacy, College of Pharmacy, Seoul National University, Seoul, Republic of Korea, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, Republic of Korea

  ⨯
• Jae-Ho Lee,

  Roles Methodology

  Affiliations Department of Pharmacy, College of Pharmacy, Seoul National University, Seoul, Republic of Korea, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, Republic of Korea

  ⨯
• Na Ryung Choi,

  Roles Resources

  Affiliation Department of Internal Medicine, Ewha Womans University College of Medicine, Division of Gastroenterology and Hepatology, Ewha Womans University Mokdong Hospital, Seoul, Republic of Korea

  ⨯
• Han Ah Lee,

  Roles Resources

  Affiliation Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Republic of Korea

  ⨯
• Hwang-Phill Kim,

  Roles Data curation, Formal analysis, Methodology

  Affiliation IMBdx, Seoul, Republic of Korea

  ⨯
• Sang-Hyun Song,

  Roles Formal analysis, Methodology

  Affiliation IMBdx, Seoul, Republic of Korea

  ⨯
• Hwi Young Kim ,

  Roles Funding acquisition, Resources, Supervision, Visualization

  * E-mail: hwiyoung@gmail.com (HYK), kimty@snu.ac.kr (T-YK), jwl@snu.ac.kr (JWL)

  Affiliation Department of Internal Medicine, Ewha Womans University College of Medicine, Division of Gastroenterology and Hepatology, Ewha Womans University Mokdong Hospital, Seoul, Republic of Korea

  ⨯
• Tae-You Kim ,

  Roles Conceptualization, Funding acquisition, Project administration

  * E-mail: hwiyoung@gmail.com (HYK), kimty@snu.ac.kr (T-YK), jwl@snu.ac.kr (JWL)

  Affiliations IMBdx, Seoul, Republic of Korea, Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea

  ⨯
• Jung Weon Lee

  Roles Funding acquisition, Project administration, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: hwiyoung@gmail.com (HYK), kimty@snu.ac.kr (T-YK), jwl@snu.ac.kr (JWL)

  Affiliations Department of Pharmacy, College of Pharmacy, Seoul National University, Seoul, Republic of Korea, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, Republic of Korea

  https://orcid.org/0000-0003-2722-8200

  ⨯