Dual effects of indoxyl sulfate on modulation of human hepatic CYP3A activity, with individual differences

• Masao Togao ,

  Roles Conceptualization, Data curation, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: masao-togao@yakult.co.jp

  Affiliation Safety Research Department, Yakult Central Institute, Kunitachi-shi, Tokyo, Japan

  https://orcid.org/0000-0003-1468-9075

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• Naoyuki Asakawa,

  Roles Conceptualization, Methodology, Writing – review & editing

  Affiliation Safety Research Department, Yakult Central Institute, Kunitachi-shi, Tokyo, Japan

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• Gaku Wagai,

  Roles Conceptualization, Writing – review & editing

  Affiliation Safety Research Department, Yakult Central Institute, Kunitachi-shi, Tokyo, Japan

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• Yuki Ohta-Takada,

  Roles Conceptualization, Writing – review & editing

  Affiliation Safety Research Department, Yakult Central Institute, Kunitachi-shi, Tokyo, Japan

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• Jun Otsuka,

  Roles Conceptualization, Writing – review & editing

  Affiliation Safety Research Department, Yakult Central Institute, Kunitachi-shi, Tokyo, Japan

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• Minoru Ando,

  Roles Conceptualization, Writing – review & editing

  Affiliation Safety Research Department, Yakult Central Institute, Kunitachi-shi, Tokyo, Japan

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• Akinobu Kurita,

  Roles Conceptualization, Writing – review & editing

  Affiliation Safety Research Department, Yakult Central Institute, Kunitachi-shi, Tokyo, Japan

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• Koji Kawakami

  Roles Conceptualization, Writing – review & editing

  Affiliation Safety Research Department, Yakult Central Institute, Kunitachi-shi, Tokyo, Japan

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