Perioperative and long-term outcomes of laparoscopic liver resection for combined hepatocellular carcinoma and cholangiocarcinoma versus intrahepatic cholangiocarcinoma: A propensity score matching analysis

Chengfei Du; Hanyu Wang; Wenli Cao; Zichen Yu; Junwei Liu; Jie Liu; Liming Jin; Yunyun Feng; Fangqiang Wei

doi:10.1371/journal.pone.0328104

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Open Access

Peer-reviewed

Research Article

Perioperative and long-term outcomes of laparoscopic liver resection for combined hepatocellular carcinoma and cholangiocarcinoma versus intrahepatic cholangiocarcinoma: A propensity score matching analysis

Chengfei Du ,

Roles Conceptualization, Data curation, Formal analysis, Methodology, Writing – original draft

¶☯ The authors contributed equally to the paper.

Affiliations Department of General Surgery, Cancer center, Division of Hepatobiliary and Pancreatic Surgery, Zhejiang Provincial People’s Hospital, Affiliated People’s Hospital, Hangzhou Medical College, Hangzhou, Zhejiang Province, China, Second Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, Zhejiang Province, China
⨯
Hanyu Wang ,

Roles Conceptualization, Data curation, Formal analysis, Methodology, Writing – original draft

¶☯ The authors contributed equally to the paper.

Affiliations Department of General Surgery, Cancer center, Division of Hepatobiliary and Pancreatic Surgery, Zhejiang Provincial People’s Hospital, Affiliated People’s Hospital, Hangzhou Medical College, Hangzhou, Zhejiang Province, China, Department of Public Health, Hangzhou Medical College, Hangzhou, Zhejiang Province, China
⨯
Wenli Cao,

Roles Conceptualization, Data curation, Methodology

Affiliations Department of General Surgery, Cancer center, Division of Hepatobiliary and Pancreatic Surgery, Zhejiang Provincial People’s Hospital, Affiliated People’s Hospital, Hangzhou Medical College, Hangzhou, Zhejiang Province, China, Department of Public Health, Hangzhou Medical College, Hangzhou, Zhejiang Province, China
⨯
Zichen Yu,

Roles Conceptualization, Data curation, Formal analysis, Methodology

Affiliation Department of General Surgery, Cancer center, Division of Hepatobiliary and Pancreatic Surgery, Zhejiang Provincial People’s Hospital, Affiliated People’s Hospital, Hangzhou Medical College, Hangzhou, Zhejiang Province, China
⨯
Junwei Liu,

Roles Conceptualization, Data curation, Formal analysis, Methodology

Affiliation Department of General Surgery, Cancer center, Division of Hepatobiliary and Pancreatic Surgery, Zhejiang Provincial People’s Hospital, Affiliated People’s Hospital, Hangzhou Medical College, Hangzhou, Zhejiang Province, China
⨯
Jie Liu,

Roles Conceptualization, Data curation, Formal analysis, Methodology

Affiliation Department of General Surgery, Cancer center, Division of Hepatobiliary and Pancreatic Surgery, Zhejiang Provincial People’s Hospital, Affiliated People’s Hospital, Hangzhou Medical College, Hangzhou, Zhejiang Province, China
⨯
Liming Jin,

Roles Conceptualization, Data curation, Formal analysis, Methodology

Affiliation Department of General Surgery, Cancer center, Division of Hepatobiliary and Pancreatic Surgery, Zhejiang Provincial People’s Hospital, Affiliated People’s Hospital, Hangzhou Medical College, Hangzhou, Zhejiang Province, China
⨯
Yunyun Feng,

Roles Conceptualization, Data curation, Formal analysis, Methodology

Affiliation Department of General Surgery, Cancer center, Division of Hepatobiliary and Pancreatic Surgery, Zhejiang Provincial People’s Hospital, Affiliated People’s Hospital, Hangzhou Medical College, Hangzhou, Zhejiang Province, China
⨯
Fangqiang Wei

Roles Conceptualization, Data curation, Formal analysis, Methodology, Supervision, Writing – original draft, Writing – review & editing

* E-mail: wdfwfq@126.com

Affiliation Department of General Surgery, Cancer center, Division of Hepatobiliary and Pancreatic Surgery, Zhejiang Provincial People’s Hospital, Affiliated People’s Hospital, Hangzhou Medical College, Hangzhou, Zhejiang Province, China

https://orcid.org/0000-0003-0871-2275

⨯

Perioperative and long-term outcomes of laparoscopic liver resection for combined hepatocellular carcinoma and cholangiocarcinoma versus intrahepatic cholangiocarcinoma: A propensity score matching analysis

Chengfei Du,
Hanyu Wang,
Wenli Cao,
Zichen Yu,
Junwei Liu,
Jie Liu,
Liming Jin,
Yunyun Feng,
Fangqiang Wei

Published: August 18, 2025
https://doi.org/10.1371/journal.pone.0328104

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Hepatocellular carcinoma
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Hepatic resection
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Tumor resection
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Cholangiocarcinoma
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Surgical and invasive medical procedures
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