Non-linear association between life’s essential 8 score and depression in middle-aged and older adults with chronic obstructive pulmonary disease

Yushan Shi; Di Huang; Linlin Qu; Qingyin Liu; Zhanjun Qiu; Xianhai Chen

doi:10.1371/journal.pone.0327877

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Open Access

Peer-reviewed

Research Article

Non-linear association between life’s essential 8 score and depression in middle-aged and older adults with chronic obstructive pulmonary disease

Yushan Shi,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources, Software, Supervision, Validation, Visualization, Writing – original draft

Affiliations Shandong University of Traditional Chinese Medicine, Jinan, China, Department of laboratory, The Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, China

https://orcid.org/0000-0003-3951-2751

⨯
Di Huang,

Roles Data curation, Formal analysis, Investigation, Methodology, Resources, Software, Supervision, Validation, Visualization

Affiliations Shandong University of Traditional Chinese Medicine, Jinan, China, Department of Respiratory and Critical Care Medicine, The Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, China
⨯
Linlin Qu,

Roles Data curation, Formal analysis, Investigation, Methodology, Software, Supervision, Validation, Visualization

Affiliation Shandong University of Traditional Chinese Medicine, Jinan, China
⨯
Qingyin Liu,

Roles Data curation, Formal analysis, Investigation, Methodology, Resources, Software, Supervision, Validation, Visualization

Affiliation Shandong University of Traditional Chinese Medicine, Jinan, China
⨯
Zhanjun Qiu ,

Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Resources, Supervision, Visualization, Writing – review & editing

* E-mail: qiuzhj227@163.com (ZQ); chenxianhai18@163.com (XC)

Affiliation Gerontology Department, The Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, China
⨯
Xianhai Chen

Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Resources, Supervision, Validation, Visualization, Writing – review & editing

* E-mail: qiuzhj227@163.com (ZQ); chenxianhai18@163.com (XC)

Affiliation Department of Respiratory and Critical Care Medicine, The Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, China
⨯

Non-linear association between life’s essential 8 score and depression in middle-aged and older adults with chronic obstructive pulmonary disease

Yushan Shi,
Di Huang,
Linlin Qu,
Qingyin Liu,
Zhanjun Qiu,
Xianhai Chen

Published: July 28, 2025
https://doi.org/10.1371/journal.pone.0327877

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