Desmin disorganisation: A key feature in feline hypertrophic cardiomyopathy

Wan-Ching Cheng; Charlotte Lawson; Lois Wilkie; Melanie Dobromylsky; Virginia Luis Fuentes; Mark R. Holt; Elisabeth Ehler; David J. Connolly

doi:10.1371/journal.pone.0327850

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Open Access

Peer-reviewed

Research Article

Desmin disorganisation: A key feature in feline hypertrophic cardiomyopathy

Wan-Ching Cheng,

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Writing – original draft

Affiliation Department of Clinical Science and Services, Royal Veterinary College, Hatfield, Hertfordshire, United Kingdom
⨯
Charlotte Lawson,

Roles Formal analysis, Investigation, Methodology, Supervision

Affiliation Department of Comparative Biomedical Sciences, Royal Veterinary College, Royal College Street London, United Kingdom
⨯
Lois Wilkie,

Roles Data curation, Investigation, Methodology

Affiliation Department of Clinical Science and Services, Royal Veterinary College, Hatfield, Hertfordshire, United Kingdom
⨯
Melanie Dobromylsky,

Roles Data curation, Investigation, Methodology, Resources

Affiliation Finn Pathologists, Harleston, Norfolk, United Kingdom
⨯
Virginia Luis Fuentes,

Roles Conceptualization, Supervision, Writing – review & editing

Affiliation Department of Clinical Science and Services, Royal Veterinary College, Hatfield, Hertfordshire, United Kingdom
⨯
Mark R. Holt,

Roles Data curation, Formal analysis, Investigation, Writing – review & editing

Affiliation British Heart Foundation Centre of Research Excellence, School of Cardiovascular and Metabolic Medicine and Sciences, King’s College London, London, United Kingdom
⨯
Elisabeth Ehler ,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources, Supervision, Writing – review & editing

¶‡ EE and DJC are joint senior authors on this work.

Affiliation British Heart Foundation Centre of Research Excellence, School of Cardiovascular and Metabolic Medicine and Sciences, King’s College London, London, United Kingdom

https://orcid.org/0000-0001-5646-5964

⨯
David J. Connolly

Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – review & editing

* E-mail: dconnolly@rvc.ac.uk

¶‡ EE and DJC are joint senior authors on this work.

Affiliation Department of Clinical Science and Services, Royal Veterinary College, Hatfield, Hertfordshire, United Kingdom

https://orcid.org/0000-0003-2129-1874

⨯

Desmin disorganisation: A key feature in feline hypertrophic cardiomyopathy

Wan-Ching Cheng,
Charlotte Lawson,
Lois Wilkie,
Melanie Dobromylsky,
Virginia Luis Fuentes,
Mark R. Holt,
Elisabeth Ehler,
David J. Connolly

Published: July 14, 2025
https://doi.org/10.1371/journal.pone.0327850

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Desmin
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Cats
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Cytoskeletal proteins
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