Distribution of chronic wasting disease (CWD) prions in tissues from experimentally exposed coyotes (Canis latrans)

Nancy Ho; Reece McGinn; Paulina Soto; Terry R. Spraker; Justin Fischer; Kurt VerCauteren; Tracy Nichols; Rodrigo Morales

doi:10.1371/journal.pone.0327485

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Open Access

Peer-reviewed

Research Article

Distribution of chronic wasting disease (CWD) prions in tissues from experimentally exposed coyotes (Canis latrans)

Nancy Ho,

Roles Data curation, Formal analysis, Investigation, Writing – original draft

Affiliation Department of Neurology, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America
⨯
Reece McGinn,

Roles Investigation, Validation

Affiliation Department of Neurology, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America

https://orcid.org/0009-0007-7354-8367

⨯
Paulina Soto,

Roles Supervision, Writing – original draft

Affiliations Department of Neurology, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America, Centro Integrativo de Biologia y Quimica Aplicada (CIBQA). Universidad Bernardo O’Higgins. Santiago, Chile
⨯
Terry R. Spraker,

Roles Investigation

Affiliation Colorado State University Diagnostic Medical Center, College of Veterinary Medicine and Biomedical Sciences, Colorado State University. Fort Collins, Colorado, United States of America
⨯
Justin Fischer,

Roles Investigation, Writing – review & editing

Affiliation United States Department of Agriculture, Animal Plant Health Inspection Service, Wildlife Services. Fort Collins, Colorado, United States of America
⨯
Kurt VerCauteren,

Roles Investigation, Writing – review & editing

Affiliation United States Department of Agriculture, Animal Plant Health Inspection Service, Wildlife Services. Fort Collins, Colorado, United States of America
⨯
Tracy Nichols,

Roles Conceptualization, Investigation, Writing – review & editing

Affiliation United States Department of Agriculture, Animal Plant Health Inspection Service, Veterinary Services. Fort Collins, Colorado, United States of America
⨯
Rodrigo Morales

Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – original draft

* E-mail: Rodrigo.MoralesLoyola@uth.tmc.edu

Affiliations Department of Neurology, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America, Centro Integrativo de Biologia y Quimica Aplicada (CIBQA). Universidad Bernardo O’Higgins. Santiago, Chile

https://orcid.org/0000-0001-7766-5770

⨯

Distribution of chronic wasting disease (CWD) prions in tissues from experimentally exposed coyotes (Canis latrans)

Nancy Ho,
Reece McGinn,
Paulina Soto,
Terry R. Spraker,
Justin Fischer,
Kurt VerCauteren,
Tracy Nichols,
Rodrigo Morales

Published: July 9, 2025
https://doi.org/10.1371/journal.pone.0327485

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Prions
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Coyotes
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Chronic wasting disease
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Animal prion diseases
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