ECDD-S16, a synthetic derivative of cleistanthin A, suppresses pyroptosis in Burkholderia pseudomallei-infected U937 macrophages

• Suphasuta Khongpraphan,

  Roles Formal analysis, Investigation, Validation, Writing – original draft

  Affiliations Department of Microbiology, Faculty of Science, Mahidol University, Bangkok, Thailand, Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand

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• Sucharat Sanongkiet,

  Roles Formal analysis, Investigation, Validation

  Affiliation Department of Chemistry, Faculty of Science, Silpakorn University, Nakhon Pathom, Thailand

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• Chularat Luangjindarat,

  Roles Formal analysis, Investigation, Validation

  Affiliations Department of Microbiology, Faculty of Science, Mahidol University, Bangkok, Thailand, Division of Medical Bioinformatics, Research Department, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand

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• Sarut Thairat,

  Roles Formal analysis

  Affiliation Oral Tissues, Cells and Molecular Biology Analysis and Research Center, Faculty of Dentistry, Mahidol University, Bangkok, Thailand

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• Bumrung Munyoo,

  Roles Investigation, Methodology

  Affiliation Excellence Center for Drug Discovery (ECDD), Faculty of Science, Mahidol University, Bangkok, Thailand

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• Napason Chabang,

  Roles Investigation, Methodology

  Affiliation School of Bioinnovation and Bio-Based Product Intelligence, Faculty of Science, Mahidol University, Bangkok, Thailand

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• Sitthivut Charoensutthivarakul,

  Roles Investigation, Methodology

  Affiliations Excellence Center for Drug Discovery (ECDD), Faculty of Science, Mahidol University, Bangkok, Thailand, School of Bioinnovation and Bio-Based Product Intelligence, Faculty of Science, Mahidol University, Bangkok, Thailand, Center for Neuroscience, Faculty of Science, Mahidol University, Bangkok, Thailand

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• Suparerk Borwornpinyo,

  Roles Investigation, Methodology

  Affiliations Excellence Center for Drug Discovery (ECDD), Faculty of Science, Mahidol University, Bangkok, Thailand, Department of Biotechnology, Faculty of Science, Mahidol University, Bangkok, Thailand

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• Patoomratana Tuchinda,

  Roles Investigation, Methodology

  Affiliation Excellence Center for Drug Discovery (ECDD), Faculty of Science, Mahidol University, Bangkok, Thailand

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• Marisa Ponpuak,

  Roles Supervision, Writing – review & editing

  Affiliation Department of Microbiology, Faculty of Science, Mahidol University, Bangkok, Thailand

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• Pongsak Utaisincharoen ,

  Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

  * E-mail: matsayapan.pud@mahidol.ac.th (MP); pongsak.uta@mahidol.ac.th (PU)

  Affiliation Department of Microbiology, Faculty of Science, Mahidol University, Bangkok, Thailand

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• Matsayapan Pudla

  Roles Conceptualization, Funding acquisition, Investigation, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: matsayapan.pud@mahidol.ac.th (MP); pongsak.uta@mahidol.ac.th (PU)

  Affiliation Department of Oral Microbiology, Faculty of Dentistry, Mahidol University, Bangkok, Thailand

  https://orcid.org/0000-0001-8807-4124

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