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Study Protocol
Study protocol for the Health Outcomes in Pregnancy and Early Childhood (HOPE) Study: A mother-infant study in American Samoa
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Lacey W. Heinsberg ,
Contributed equally to this work with: Lacey W. Heinsberg, Miracle Loia
Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing
* E-mail: law145@pitt.edu
Affiliations Department of Health Promotion and Development, School of Nursing, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, Department of Human Genetics, School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, Obesity, Lifestyle, and Genetic Adaptations (OLaGA) Study Group
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Miracle Loia ,
Contributed equally to this work with: Lacey W. Heinsberg, Miracle Loia
Roles Conceptualization, Methodology, Project administration, Writing – original draft, Writing – review & editing
Affiliation Obesity, Lifestyle, and Genetic Adaptations (OLaGA) Study Group
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Susie Tasele,
Roles Methodology, Writing – review & editing
Affiliation Obesity, Lifestyle, and Genetic Adaptations (OLaGA) Study Group
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Kima Faasalele-Savusa,
Roles Methodology, Project administration, Supervision, Writing – review & editing
Affiliation Obesity, Lifestyle, and Genetic Adaptations (OLaGA) Study Group
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Jenna C. Carlson,
Roles Funding acquisition, Methodology, Writing – review & editing
Affiliations Department of Human Genetics, School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, Obesity, Lifestyle, and Genetic Adaptations (OLaGA) Study Group, Department of Biostatistics and Health Data Science, School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
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Scott Anesi,
Roles Resources, Supervision, Writing – review & editing
Affiliation Lyndon B Johnson Tropical Medical Center, Faga’alu, American Samoa
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Katie Desobry,
Roles Project administration, Writing – review & editing
Affiliation Lyndon B Johnson Tropical Medical Center, Faga’alu, American Samoa
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Efren Yuchongco,
Roles Resources, Writing – review & editing
Affiliation Lyndon B Johnson Tropical Medical Center, Faga’alu, American Samoa
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Brian Fortuno Guevara,
Roles Resources, Writing – review & editing
Affiliation Lyndon B Johnson Tropical Medical Center, Faga’alu, American Samoa
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Aigaeiva Sesaga,
Roles Resources, Writing – review & editing
Affiliation Lyndon B Johnson Tropical Medical Center, Faga’alu, American Samoa
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Alice Iloilo,
Roles Resources, Writing – review & editing
Affiliation Lyndon B Johnson Tropical Medical Center, Faga’alu, American Samoa
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Va’atausili Tofaeono,
Roles Resources, Writing – review & editing
Affiliations American Samoa Community Cancer Coalition, Nu’uuli, American Samoa, Department of Indigenous Health, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, North Dakota, United States of America
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Kaylynn Bryan,
Roles Methodology, Project administration, Writing – review & editing
Affiliation Department of Health Promotion and Development, School of Nursing, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
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Tina Tauasosi-Posiulai,
Roles Methodology, Writing – review & editing
Affiliation Department of Tropical Medicine, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, Hawaii, United States of America
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Erin E. Kershaw,
Roles Funding acquisition, Methodology, Writing – review & editing
Affiliations Obesity, Lifestyle, and Genetic Adaptations (OLaGA) Study Group, Division of Endocrinology and Metabolism, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
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Yvette P. Conley,
Roles Conceptualization, Funding acquisition, Writing – review & editing
Affiliations Department of Health Promotion and Development, School of Nursing, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, Department of Human Genetics, School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
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Daniel E. Weeks,
Roles Conceptualization, Funding acquisition, Methodology, Supervision, Writing – review & editing
Affiliations Department of Human Genetics, School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, Obesity, Lifestyle, and Genetic Adaptations (OLaGA) Study Group, Department of Biostatistics and Health Data Science, School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
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Nicola L. Hawley ,
Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing – review & editing
¶‡ NLH and BTM-H also contributed equally to this work.
Affiliations Obesity, Lifestyle, and Genetic Adaptations (OLaGA) Study Group, Department of Chronic Disease Epidemiology, Yale University School of Public Health, New Haven, Connecticut, United States of America
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Bethel T. Muasau-Howard
Roles Conceptualization, Methodology, Project administration, Supervision, Writing – review & editing
¶‡ NLH and BTM-H also contributed equally to this work.
Affiliations Obesity, Lifestyle, and Genetic Adaptations (OLaGA) Study Group, Lyndon B Johnson Tropical Medical Center, Faga’alu, American Samoa
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Study protocol for the Health Outcomes in Pregnancy and Early Childhood (HOPE) Study: A mother-infant study in American Samoa
- Lacey W. Heinsberg,
- Miracle Loia,
- Susie Tasele,
- Kima Faasalele-Savusa,
- Jenna C. Carlson,
- Scott Anesi,
- Katie Desobry,
- Efren Yuchongco,
- Brian Fortuno Guevara,
- Aigaeiva Sesaga
- Published: September 15, 2025
- https://doi.org/10.1371/journal.pone.0326644