Trends of long-term opioid therapy and subsequent discontinuation among people with chronic non-cancer pain in UK primary care: A retrospective cohort study

• Qian Cai ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: qian.cai@manchester.ac.uk

  Affiliation Division of Informatics, Imaging & Data Sciences, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom

  https://orcid.org/0000-0002-6052-5664

  ⨯
• Yun-Ting Huang,

  Roles Conceptualization, Methodology, Resources, Supervision, Writing – review & editing

  Affiliations Division of Informatics, Imaging & Data Sciences, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom, Centre for Pharmacoepidemiology and Drug Safety, Division of Pharmacy and Optometry, University of Manchester, Manchester, United Kingdom

  ⨯
• Thomas Allen,

  Roles Conceptualization, Methodology, Resources, Supervision, Validation, Writing – review & editing

  Affiliation Centre for Health Economics, Division of Population Health, Health Services Research and Primary Care, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom

  https://orcid.org/0000-0002-2972-7911

  ⨯
• Charlotte Morris,

  Roles Conceptualization, Resources, Validation, Writing – review & editing

  Affiliations Division of Population Health, Health Services Research & Primary Care, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom, National Institute for Health and Care Research (NIHR) School for Primary Care Research, Division of Population Health, Health Services Research and Primary Care, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom, NIHR Greater Manchester Patient Safety Research Collaboration, University of Manchester, Manchester, United Kingdom

  ⨯
• Christos Grigoroglou,

  Roles Conceptualization, Methodology, Resources, Supervision, Validation, Writing – review & editing

  Affiliation Centre for Health Economics, Division of Population Health, Health Services Research and Primary Care, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom

  ⨯
• Evangelos Kontopantelis

  Roles Conceptualization, Methodology, Project administration, Resources, Software, Supervision, Validation, Writing – review & editing

  Affiliations Division of Informatics, Imaging & Data Sciences, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom, National Institute for Health and Care Research (NIHR) School for Primary Care Research, Division of Population Health, Health Services Research and Primary Care, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom

  https://orcid.org/0000-0001-6450-5815

  ⨯