Next-Generation Sequencing (NGS) in non-small cell lung carcinoma: A real-world experience in the public health system of Galicia (Northwest Spain)

Ihab Abdulkader-Nallib; José Manuel Cameselle-Teijeiro; Iván Lesende-Rodríguez; Raquel Pérez-Becerra; José Ramón Antúnez-López; Jorge García-González; Luis León-Mateos; María Sánchez-Ares

doi:10.1371/journal.pone.0326336

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Open Access

Peer-reviewed

Research Article

Next-Generation Sequencing (NGS) in non-small cell lung carcinoma: A real-world experience in the public health system of Galicia (Northwest Spain)

Ihab Abdulkader-Nallib ,

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: m.sanchez.ares@gmail.com (MSA); ihab.abdulkader.nallib@sergas.es (IAN)

Affiliations Department of Pathology, Clinical University Hospital of Santiago de Compostela, Health Research Institute of Santiago de Compostela, Galician Healthcare Service (SERGAS), Santiago de Compostela, Spain, School of Medicine, University of Santiago de Compostela, Santiago de Compostela, Spain
⨯
José Manuel Cameselle-Teijeiro,

Roles Formal analysis, Funding acquisition, Investigation, Resources, Writing – review & editing

Affiliations Department of Pathology, Clinical University Hospital of Santiago de Compostela, Health Research Institute of Santiago de Compostela, Galician Healthcare Service (SERGAS), Santiago de Compostela, Spain, School of Medicine, University of Santiago de Compostela, Santiago de Compostela, Spain

https://orcid.org/0000-0002-5516-8914

⨯
Iván Lesende-Rodríguez,

Roles Investigation, Methodology, Software, Validation, Writing – review & editing

Affiliation University of A Coruña, A Coruña, Spain

https://orcid.org/0009-0000-1104-6141

⨯
Raquel Pérez-Becerra,

Roles Investigation, Validation, Writing – review & editing

Affiliation Department of Pathology, Clinical University Hospital of Santiago de Compostela, Health Research Institute of Santiago de Compostela, Galician Healthcare Service (SERGAS), Santiago de Compostela, Spain
⨯
José Ramón Antúnez-López,

Roles Investigation, Resources, Writing – review & editing

Affiliations Department of Pathology, Clinical University Hospital of Santiago de Compostela, Health Research Institute of Santiago de Compostela, Galician Healthcare Service (SERGAS), Santiago de Compostela, Spain, School of Medicine, University of Santiago de Compostela, Santiago de Compostela, Spain
⨯
Jorge García-González,

Roles Investigation, Resources, Writing – review & editing

Affiliations Department of Medical Oncology, Clinical University Hospital of Santiago de Compostela, Galician Healthcare Service (SERGAS), Santiago de Compostela, Spain, ONCOMET, Health Research Institute of Santiago de Compostela (IDIS), Santiago de Compostela, Spain, The Spanish Biomedical Research Centre in Cancer (CIBERONC), Madrid, Spain

https://orcid.org/0000-0001-7672-9867

⨯
Luis León-Mateos,

Roles Investigation, Resources, Writing – review & editing

Affiliations Department of Medical Oncology, Clinical University Hospital of Santiago de Compostela, Galician Healthcare Service (SERGAS), Santiago de Compostela, Spain, ONCOMET, Health Research Institute of Santiago de Compostela (IDIS), Santiago de Compostela, Spain, The Spanish Biomedical Research Centre in Cancer (CIBERONC), Madrid, Spain

https://orcid.org/0000-0002-0742-1209

⨯
María Sánchez-Ares

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: m.sanchez.ares@gmail.com (MSA); ihab.abdulkader.nallib@sergas.es (IAN)

Affiliation Department of Pathology, Clinical University Hospital of Santiago de Compostela, Health Research Institute of Santiago de Compostela, Galician Healthcare Service (SERGAS), Santiago de Compostela, Spain

https://orcid.org/0000-0003-0098-4161

⨯

Next-Generation Sequencing (NGS) in non-small cell lung carcinoma: A real-world experience in the public health system of Galicia (Northwest Spain)

Ihab Abdulkader-Nallib,
José Manuel Cameselle-Teijeiro,
Iván Lesende-Rodríguez,
Raquel Pérez-Becerra,
José Ramón Antúnez-López,
Jorge García-González,
Luis León-Mateos,
María Sánchez-Ares

Published: July 1, 2025
https://doi.org/10.1371/journal.pone.0326336

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Non-small cell lung cancer
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Next-generation sequencing
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Mutation detection
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Reverse transcriptase-polymerase chain reaction
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Point mutation
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Insertion mutation
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Tyrosine kinases
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Fluorescent in situ hybridization
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