The challenges of replication: A worked example of methods reproducibility using electronic health record data

• Richard Williams ,

  Roles Conceptualization, Data curation, Investigation, Methodology, Writing – original draft, Writing – review & editing

  * E-mail: richard.williams@phc.ox.ac.uk

  Affiliations Division of Informatics, Imaging and Data Science, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom, NIHR Applied Research Collaboration Greater Manchester, Manchester Academic Health Science Centre, University of Manchester, Manchester, United Kingdom

  https://orcid.org/0000-0002-0920-1103

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• Thomas Bolton,

  Roles Methodology, Writing – review & editing

  Affiliation British Heart Foundation Data Science Centre, Health Data Research UK, London, United Kingdom

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• David Jenkins,

  Roles Methodology, Writing – review & editing

  Affiliation Division of Informatics, Imaging and Data Science, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom

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• Mehrdad A. Mizani,

  Roles Methodology, Writing – review & editing

  Affiliations British Heart Foundation Data Science Centre, Health Data Research UK, London, United Kingdom, Institute of Health Informatics, University College London, London, United Kingdom

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• Matthew Sperrin,

  Roles Methodology, Writing – review & editing

  Affiliation Division of Informatics, Imaging and Data Science, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom

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• Cathie Sudlow,

  Roles Methodology, Writing – review & editing

  Affiliation British Heart Foundation Data Science Centre, Health Data Research UK, London, United Kingdom

  https://orcid.org/0000-0002-7725-7520

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• Angela Wood,

  Roles Conceptualization, Methodology, Writing – review & editing

  Affiliations British Heart Foundation Data Science Centre, Health Data Research UK, London, United Kingdom, Department of Public Health and Primary Care, British Heart Foundation Cardiovascular Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom, Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge, United Kingdom, Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, United Kingdom

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• Adrian Heald,

  Roles Methodology, Writing – review & editing

  Affiliation Department of Diabetes and Endocrinology, Salford Royal NHS Foundation Trust, Salford, United Kingdom

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• Niels Peek,

  Roles Methodology, Supervision, Writing – review & editing

  Affiliations Division of Informatics, Imaging and Data Science, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom, Department of Public Health and Primary Care, The Healthcare Improvement Studies Institute (THIS Institute), University of Cambridge, Cambridge, United Kingdom

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• on behalf of the CVD-COVID-UK/COVID-IMPACT Consortium

  ¶A full list of consortium members is available in the Acknowledgements.

  Affiliation Division of Informatics, Imaging and Data Science, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom

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