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Open Access
Peer-reviewed
Research Article
Associations between physical activity and CVD-related metabolomic and proteomic biomarkers
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Örjan Ekblom ,
Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing
* E-mail: orjan.ekblom@gih.se
Affiliations Department of Physical Activity and Health, The Swedish School of Sport and Health Sciences (GIH), Stockholm, Sweden, Department of Neurobiology, Care Sciences and Society, Division of Nursing, Karolinska Institutet, Stockholm, Sweden
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Harry Björkbacka,
Roles Conceptualization, Methodology, Writing – original draft, Writing – review & editing
Affiliation Department of Clinical Sciences in Malmö, Lund University, Malmö, Sweden
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Mats Börjesson,
Roles Conceptualization, Methodology, Writing – original draft, Writing – review & editing
Affiliations Center for Lifestyle Intervention, Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden, Sahlgrenska University Hospital, Region Västra Götaland, Gothenburg, Sweden
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Elin Ekblom-Bak,
Roles Conceptualization, Methodology, Writing – original draft, Writing – review & editing
Affiliation Department of Physical Activity and Health, The Swedish School of Sport and Health Sciences (GIH), Stockholm, Sweden
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Anders Blomberg,
Roles Methodology, Writing – review & editing
Affiliation Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden
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Kenneth Caidahl,
Roles Methodology, Writing – review & editing
Affiliations Department of Clinical Physiology, Karolinska University Hospital, and Karolinska Institutet, Stockholm, Sweden, Department of Clinical Physiology, Sahlgrenska University Hospital, and Sahlgrenska Academy, Gothenburg, Sweden
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Ewa Ehrenborg,
Roles Methodology, Writing – review & editing
Affiliation Cardiovascular Medicine Unit, Department of Medicine, Center for Molecular Medicine, Karolinska Institute and Karolinska University Hospital, Stockholm, Sweden
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Gunnar Engström,
Roles Methodology, Writing – review & editing
Affiliation Department of Clinical Sciences in Malmö, Lund University, Malmö, Sweden
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Jan Engvall,
Roles Methodology, Writing – review & editing
Affiliations CMIV, Centre of Medical Image Science and Visualization, Linköping University, Linköping, Sweden, Department of Clinical Physiology, and Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden
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David Erlinge,
Roles Methodology, Writing – review & editing
Affiliation Department of Clinical Sciences Lund, Cardiology, Lund University, and Skåne University Hospital, Lund, Sweden
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Tove Fall,
Roles Methodology, Writing – review & editing
Affiliation Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala, Sweden
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Bruna Gigante,
Roles Methodology, Writing – review & editing
Affiliations Division of Cardiovascular Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Sweden, Department of Cardiology, Danderyds Hospital, Stockholm, Sweden
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Anders Gummesson,
Roles Methodology, Writing – review & editing
Affiliations Department of Clinical Genetics and Genomics, Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden, Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
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Tomas Jernberg,
Roles Methodology, Writing – review & editing
Affiliation Department of Clinical Sciences, Danderyd University Hospital, Karolinska Institutet, Stockholm, Sweden
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Lars Lind,
Roles Methodology, Writing – review & editing
Affiliation Department of Medical Sciences, Clinical Epidemiology, University of Uppsala, Uppsala, Sweden
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David Molnar,
Roles Methodology, Writing – review & editing
Affiliations Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden, Department of Radiology, Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden
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Jonas Oldgren,
Roles Methodology, Writing – review & editing
Affiliations Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden, Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden
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Aidin Rawshani,
Roles Methodology, Writing – review & editing
Affiliations Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden, Wallenberg Laboratory for Cardiovascular and Metabolic Research, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden
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Johan Sundström,
Roles Methodology, Writing – review & editing
Affiliations Department of Medical Sciences, Uppsala University, Uppsala, Sweden, The George Institute for Global Health, University of New South Wales, Sydney, Australia
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Stefan Söderberg,
Roles Methodology, Writing – review & editing
Affiliation Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden
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Patrik Wennberg,
Roles Methodology, Writing – review & editing
Affiliation Department of Public Health and Clinical Medicine, Family Medicine, Umeå University, Umeå, Sweden
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Carl Johan Östgren
Roles Conceptualization, Investigation, Methodology, Writing – original draft, Writing – review & editing
Affiliations CMIV, Centre of Medical Image Science and Visualization, Linköping University, Linköping, Sweden, Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden
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Associations between physical activity and CVD-related metabolomic and proteomic biomarkers
- Örjan Ekblom,
- Harry Björkbacka,
- Mats Börjesson,
- Elin Ekblom-Bak,
- Anders Blomberg,
- Kenneth Caidahl,
- Ewa Ehrenborg,
- Gunnar Engström,
- Jan Engvall,
- David Erlinge
- Published: June 11, 2025
- https://doi.org/10.1371/journal.pone.0325720