The tumor suppressor FAT1 controls YAP/TAZ protein degradation and tumor cell proliferation through E3 ligase MIB2

• Rui Li,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Validation, Visualization, Writing – original draft

  Current address: TRON – Translational Oncology at the University Medical Center of the Johannes Gutenberg University gGmbH, Mainz, Germany

  Affiliation Department of Pharmacology, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany

  ⨯
• Boris Strilic,

  Roles Methodology

  Current address: TRON – Translational Oncology at the University Medical Center of the Johannes Gutenberg University gGmbH, Mainz, Germany

  Affiliation Department of Pharmacology, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany

  ⨯
• Young-June Jin,

  Roles Data curation, Methodology

  Affiliation Department of Pharmacology, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany

  ⨯
• Jingchen Shao,

  Roles Data curation, Methodology

  Affiliation Department of Pharmacology, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany

  https://orcid.org/0000-0002-5305-2344

  ⨯
• Yundong Peng,

  Roles Data curation, Visualization

  Affiliation Department of Cardiac Development and Remodeling, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany

  ⨯
• Lei Wang,

  Roles Methodology

  Affiliation Department of Pharmacology, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany

  ⨯
• Qi Quan,

  Roles Methodology

  Affiliation Department of Pharmacology, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany

  ⨯
• Zhiyong Wang,

  Roles Resources

  Affiliation Moores Cancer Center, University of California, San Diego, La Jolla, California, United States of America

  ⨯
• Johannes Graumann,

  Roles Data curation, Methodology

  Affiliations Biomolecular Mass Spectrometry Service Group, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany, Department of Medicine, Institute of Translational Proteomics, Philipps-University Marburg, Marburg, Germany

  ⨯
• J. Silvio Gutkind,

  Roles Resources

  Affiliations Moores Cancer Center, University of California, San Diego, La Jolla, California, United States of America, Department of Pharmacology, University of California San Diego, La Jolla, California, United States of America

  ⨯
• Nina Wettschureck,

  Roles Supervision

  Affiliations Department of Pharmacology, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany, Center for Molecular Medicine, Goethe University Frankfurt, Frankfurt, Germany

  ⨯
• Stefan Offermanns

  Roles Conceptualization, Supervision, Writing – review & editing

  * E-mail: stefan.offermanns@mpi-bn.mpg.de

  Affiliations Department of Pharmacology, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany, Center for Molecular Medicine, Goethe University Frankfurt, Frankfurt, Germany, Frankfurt Cancer Institute, Goethe University Frankfurt, Frankfurt, Germany

  https://orcid.org/0000-0001-8676-6805

  ⨯