Impact of mtG3PDH inhibitors on proliferation and metabolism of androgen receptor-negative prostate cancer cells: Role of extracellular pyruvate

• Floriana Jessica Di Paola,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Institute of Veterinary Physiology and Biochemistry, Justus Liebig University of Giessen, Giessen, Germany, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy,

  https://orcid.org/0000-0003-3110-3865

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• Luiza HD Cardoso,

  Roles Data curation, Visualization, Writing – review & editing

  Affiliation Oroboros Instruments, Schoepfstrasse 18, Innsbruck, Austria,

  https://orcid.org/0000-0001-6392-9229

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• Efterpi Nikitopoulou,

  Roles Data curation, Formal analysis, Investigation, Writing – review & editing

  Affiliation Medical Research Council Cancer Unit, University of Cambridge, Hutchison/MRC Research Centre, Cambridge Biomedical Campus, Cambridge, United Kingdom

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• Bianca Kulik,

  Roles Resources

  Affiliation Institute of Veterinary Physiology and Biochemistry, Justus Liebig University of Giessen, Giessen, Germany

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• Sandra Rühl,

  Roles Resources

  Affiliation Institute of Veterinary Physiology and Biochemistry, Justus Liebig University of Giessen, Giessen, Germany

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• Alexander Eva,

  Roles Resources

  Affiliation Institute of Veterinary Physiology and Biochemistry, Justus Liebig University of Giessen, Giessen, Germany

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• Natascha Sommer,

  Roles Resources, Writing – review & editing

  Affiliation Excellence Cluster Cardio-Pulmonary Institute (CPI), University of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Justus Liebig University, Giessen, Germany

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• Thomas Linn,

  Roles Writing – review & editing

  Affiliation Clinical Research Unit, Center of Internal Medicine, Justus Liebig University, Giessen, Germany

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• Erich Gnaiger,

  Roles Resources, Supervision, Writing – review & editing

  Affiliation Oroboros Instruments, Schoepfstrasse 18, Innsbruck, Austria,

  https://orcid.org/0000-0003-3647-5895

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• Klaus Failing,

  Roles Formal analysis

  Affiliation Unit for Biomathematics and Data Processing, Veterinary Faculty, Justus Liebig University of Giessen, Giessen, Germany

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• Kathrin Büttner,

  Roles Formal analysis

  Affiliation Unit for Biomathematics and Data Processing, Veterinary Faculty, Justus Liebig University of Giessen, Giessen, Germany

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• Christian Frezza,

  Roles Resources, Supervision, Writing – review & editing

  Affiliations Medical Research Council Cancer Unit, University of Cambridge, Hutchison/MRC Research Centre, Cambridge Biomedical Campus, Cambridge, United Kingdom, Faculty of Medicine and University Hospital Cologne, Faculty of Mathematics and Natural Sciences, Cluster of Excellence Cellular Stress Responses in Aging-associated Diseases (CECAD), University of Cologne, Cologne, Germany

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• Sybille Mazurek

  Roles Conceptualization, Funding acquisition, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: Sybille.Mazurek@vetmed.uni-giessen.de

  Affiliation Institute of Veterinary Physiology and Biochemistry, Justus Liebig University of Giessen, Giessen, Germany

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