Understanding the interaction of upper respiratory tract infection with respiratory syncytial virus and Streptococcus pneumoniae using a human challenge model: a multicenter, randomized controlled study protocol

• Sanjita Brito-Mutunayagam ,

  Contributed equally to this work with: Sanjita Brito-Mutunayagam, David O. Hamilton, Elena Mitsi, Carla Solórzano

  Roles Investigation, Methodology, Resources, Visualization, Writing – original draft, Writing – review & editing

  ¶These authors contributed equally to this work.

  Affiliation Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, United Kingdom

  https://orcid.org/0009-0008-3715-2493

  ⨯
• David O. Hamilton ,

  Contributed equally to this work with: Sanjita Brito-Mutunayagam, David O. Hamilton, Elena Mitsi, Carla Solórzano

  Roles Investigation, Methodology, Resources, Writing – original draft, Writing – review & editing

  ¶These authors contributed equally to this work.

  Affiliation Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, United Kingdom

  ⨯
• Elena Mitsi ,

  Contributed equally to this work with: Sanjita Brito-Mutunayagam, David O. Hamilton, Elena Mitsi, Carla Solórzano

  Roles Conceptualization, Investigation, Methodology, Resources, Writing – original draft, Writing – review & editing

  ¶These authors contributed equally to this work.

  Affiliations Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, United Kingdom, Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, United Kingdom

  ⨯
• Carla Solórzano ,

  Contributed equally to this work with: Sanjita Brito-Mutunayagam, David O. Hamilton, Elena Mitsi, Carla Solórzano

  Roles Conceptualization, Investigation, Methodology, Project administration, Resources, Writing – original draft, Writing – review & editing

  ¶These authors contributed equally to this work.

  Affiliations Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, United Kingdom, Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, United Kingdom

  ⨯
• Grace Li,

  Roles Methodology, Resources, Writing – review & editing

  Affiliation Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, United Kingdom

  ⨯
• Bruno Rocha De Macedo,

  Roles Methodology, Resources, Writing – review & editing

  Affiliation Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, United Kingdom

  ⨯
• Filora Elterish,

  Roles Investigation, Resources, Writing – original draft, Writing – review & editing

  Affiliation Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, United Kingdom

  ⨯
• Xinxue Liu,

  Roles Formal analysis, Methodology

  Affiliation Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, United Kingdom

  ⨯
• Kiarash Tanha,

  Roles Formal analysis, Methodology

  Affiliation Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, United Kingdom

  ⨯
• Rachel White,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, United Kingdom

  ⨯
• Angela Hyder-Wright,

  Roles Investigation, Methodology, Resources, Writing – review & editing

  Affiliation Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, United Kingdom

  ⨯
• Bhumika Patel,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, United Kingdom

  ⨯
• Britta C. Urban,

  Roles Methodology, Writing – review & editing

  Affiliations Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, United Kingdom, Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, United Kingdom

  ⨯
• Conor Whelan,

  Roles Project administration, Writing – review & editing

  Affiliation Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, United Kingdom

  ⨯
• Hanane Trari Belhadef,

  Roles Data curation, Software, Writing – review & editing

  Affiliation Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, United Kingdom

  ⨯
• Hannah Robinson,

  Roles Methodology, Resources, Writing – review & editing

  Affiliation Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, United Kingdom

  ⨯
• Emma Plested,

  Roles Methodology, Resources, Writing – review & editing

  Affiliation Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, United Kingdom

  ⨯
• Amber Thompson,

  Roles Methodology, Writing – review & editing

  Affiliation Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, United Kingdom

  ⨯
• Maria Lahuerta,

  Roles Conceptualization, Methodology, Writing – review & editing

  Affiliation Pfizer Vaccines, Pfizer Inc, New York, New York, United States of America

  ⨯
• Isis Kanevsky,

  Roles Conceptualization, Methodology, Writing – review & editing

  Affiliation Pfizer Vaccines, Pfizer Inc, New York, New York, United States of America

  ⨯
• Kena Swanson,

  Roles Conceptualization, Methodology, Writing – review & editing

  Affiliation Pfizer Vaccines, Pfizer Inc, New York, New York, United States of America

  ⨯
• Negar Aliabadi,

  Roles Conceptualization, Methodology, Writing – review & editing

  Affiliation Pfizer Vaccines, Pfizer Inc, New York, New York, United States of America

  ⨯
• Julie Catusse,

  Roles Conceptualization, Methodology, Writing – review & editing

  Affiliation Pfizer Vaccines, Pfizer Inc, New York, New York, United States of America

  ⨯
• Christian Theilacker,

  Roles Conceptualization, Methodology, Writing – review & editing

  Affiliation Pfizer Vaccines, Pfizer Inc, New York, New York, United States of America

  ⨯
• Bradford D. Gessner,

  Roles Conceptualization, Methodology, Writing – review & editing

  Affiliation Pfizer Vaccines, Pfizer Inc, New York, New York, United States of America

  ⨯
• Natalie I. Mazur,

  Roles Methodology, Writing – review & editing

  Affiliation Department of Pediatric Infectious Diseases and Immunology, University Medical Centre Utrecht, Utrecht, Netherlands

  ⨯
• Christopher Chiu,

  Roles Methodology, Resources, Writing – review & editing

  Affiliation Department of Infectious Disease, Imperial College London, London, United Kingdom

  ⨯
• Andrea M. Collins,

  Roles Methodology, Supervision, Writing – review & editing

  Affiliations Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, United Kingdom, University Hospital Liverpool Group, Liverpool, United Kingdom

  ⨯
• Ben Morton ,

  Roles Conceptualization, Methodology, Resources, Supervision, Writing – review & editing

  ¶& These authors also contributed equally to this work.

  Affiliation Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, United Kingdom

  https://orcid.org/0000-0002-6164-2854

  ⨯
• Maheshi N. Ramasamy ,

  Roles Conceptualization, Methodology, Resources, Supervision, Writing – review & editing

  ¶& These authors also contributed equally to this work.

  Affiliation Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, United Kingdom

  ⨯
•  [ ... ],
• Daniela M. Ferreira

  Roles Conceptualization, Funding acquisition, Methodology, Resources, Supervision, Writing – review & editing

  * E-mail: daniela.ferreira@paediatrics.ox.ac.uk

  ¶& These authors also contributed equally to this work.

  Affiliations Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, United Kingdom, Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, United Kingdom

  ⨯
• [ view all ]
• [ view less ]