Analysis of the inflammatory gene expression characteristics and immune microenvironment regulatory mechanisms in the testicular tissue of patients with non-obstructive azoospermia

Qiang Ling; Mingqi Liu; Wei Xu; Chunhua Liao; Guijian Pang

doi:10.1371/journal.pone.0324948

Loading metrics

Open Access

Peer-reviewed

Research Article

Analysis of the inflammatory gene expression characteristics and immune microenvironment regulatory mechanisms in the testicular tissue of patients with non-obstructive azoospermia

Qiang Ling,

Roles Conceptualization, Data curation, Formal analysis

Affiliation Department of Urology, The Sixth Affiliated Hospital of Guangxi Medical University, The First People’s Hospital of Yulin, Yulin, Guangxi Zhuang Autonomous Region, China
⨯
Mingqi Liu,

Roles Investigation, Methodology, Project administration

Affiliation Department of Urology, The Sixth Affiliated Hospital of Guangxi Medical University, The First People’s Hospital of Yulin, Yulin, Guangxi Zhuang Autonomous Region, China
⨯
Wei Xu,

Roles Resources, Software, Visualization, Writing – original draft, Writing – review & editing

Affiliation Department of Urology, The Sixth Affiliated Hospital of Guangxi Medical University, The First People’s Hospital of Yulin, Yulin, Guangxi Zhuang Autonomous Region, China
⨯
Chunhua Liao,

Roles Conceptualization, Visualization, Writing – original draft, Writing – review & editing

Affiliation Department of Urology, The Sixth Affiliated Hospital of Guangxi Medical University, The First People’s Hospital of Yulin, Yulin, Guangxi Zhuang Autonomous Region, China
⨯
Guijian Pang

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Supervision, Visualization

* E-mail: pangguijian@163.com

Affiliation Department of Urology, The Sixth Affiliated Hospital of Guangxi Medical University, The First People’s Hospital of Yulin, Yulin, Guangxi Zhuang Autonomous Region, China

https://orcid.org/0009-0003-4736-8478

⨯

Analysis of the inflammatory gene expression characteristics and immune microenvironment regulatory mechanisms in the testicular tissue of patients with non-obstructive azoospermia

Qiang Ling,
Mingqi Liu,
Wei Xu,
Chunhua Liao,
Guijian Pang

Published: June 3, 2025
https://doi.org/10.1371/journal.pone.0324948

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Inflammation
Is the Subject Area "Inflammation" applicable to this article?

Thanks for your feedback.
Gene expression
Is the Subject Area "Gene expression" applicable to this article?

Thanks for your feedback.
Sperm
Is the Subject Area "Sperm" applicable to this article?

Thanks for your feedback.
Immune cells
Is the Subject Area "Immune cells" applicable to this article?

Thanks for your feedback.
Artemisinin
Is the Subject Area "Artemisinin" applicable to this article?

Thanks for your feedback.
Traditional Chinese medicine
Is the Subject Area "Traditional Chinese medicine" applicable to this article?

Thanks for your feedback.
Inflammatory diseases
Is the Subject Area "Inflammatory diseases" applicable to this article?

Thanks for your feedback.
Machine learning algorithms
Is the Subject Area "Machine learning algorithms" applicable to this article?

Thanks for your feedback.