Thionated levofloxacin derivative: Potential repurposing for cancer treatment and synergism with doxorubicin on doxorubicin-resistant lung cancer cells

• Hamza Abumansour ,

  Contributed equally to this work with: Hamza Abumansour, Osama H. Abusara

  Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: h.abumansour@zuj.edu.jo

  Affiliation Department of Pharmacy, Faculty of Pharmacy, Al-Zaytoonah University of Jordan, Amman, Jordan

  ⨯
• Osama H. Abusara ,

  Contributed equally to this work with: Hamza Abumansour, Osama H. Abusara

  Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Department of Pharmacy, Faculty of Pharmacy, Al-Zaytoonah University of Jordan, Amman, Jordan

  https://orcid.org/0000-0002-0856-5618

  ⨯
• Mohammad Abu-Sini,

  Roles Methodology

  Affiliation Department of Pharmacy, Faculty of Pharmacy, Al-Zaytoonah University of Jordan, Amman, Jordan

  ⨯
• Wiam Khalil,

  Roles Methodology, Writing – review & editing

  Affiliation Department of Pharmacology, School of Medicine, The University of Jordan, Amman, Jordan

  ⨯
• Ali I. M. Ibrahim,

  Roles Methodology

  Affiliation Department of Pharmacy, Faculty of Pharmacy, Al-Zaytoonah University of Jordan, Amman, Jordan

  ⨯
• Amal M. Badawoud,

  Roles Funding acquisition, Project administration, Supervision

  Affiliation Department of Pharmacy Practice, College of Pharmacy, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia

  ⨯
• Majed S. Al Yami,

  Roles Project administration, Supervision

  Affiliations Department of Pharmacy Practice, College of Pharmacy, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia, King Abdulaziz Medical City, National Guard Health Affairs, Riyadh, Saudi Arabia, King Abdullah International Medical Research Center, Riyadh, Saudi Arabia

  https://orcid.org/0000-0003-2308-8407

  ⨯
• Dina H. Abulebdah,

  Roles Methodology

  Affiliation Department of Pharmacy, Faculty of Pharmacy, Al-Zaytoonah University of Jordan, Amman, Jordan

  ⨯
• Shiraz Halloush

  Roles Methodology

  Affiliation Department of Clinical Pharmacy and Therapeutics, Faculty of Pharmacy, Applied Science Private University, Amman, Jordan

  ⨯